Reviewed, UniProtKB/Swiss-Prot Q0P9X6 (CHER_CAMJE)

Names and origin

Protein names

Recommended name:
    Chemotaxis protein methyltransferase
    EC=2.1.1.80

Gene names

Name:	cheR
Ordered Locus Names:	Cj0923c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP By similarity.
Catalytic activity	S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.
Sequence similarities	Contains 1 cheR-type methyltransferase domain.

Ontologies

Keywords
Biological process	Chemotaxis
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein-glutamate O-methyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	Chemotaxis protein methyltransferase		PRO_0000176032
Regions
	Domain	1 – 262	262	CheR-type methyltransferase
	Region	188 – 189	2	S-adenosyl-L-methionine binding By similarity
	Region	206 – 207	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	76	1	S-adenosyl-L-methionine By similarity
	Binding site	80	1	S-adenosyl-L-methionine By similarity
	Binding site	111	1	S-adenosyl-L-methionine By similarity
	Binding site	133	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0P9X6-1 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: 57B545B90AA04328	FASTA	262	30,655
	10 20 30 40 50 60 MEKKITPSEL ELNEFIKIIN EMSGIDLTDK KNILALKLNK FLEGTNTKNF SEFLGKLKSN 70 80 90 100 110 120 RQLKQETLDF VTIGETYFLR ELAQLKEIIY YAKSLEKRVN ILSAPCSSGE EVYSLALLAA 130 140 150 160 170 180 QNFIKDMYIL GVDINSSVIE KAKLGKYQGR TLQRLSESEK RRFFLESEDK FYTINKNELC 190 200 210 220 230 240 TCKFELCNVF EEKFSRLGKF DIIASRNMII YFDHESKLKL MERFHRILND KGRLYVGNAD 250 260 LIPETIYFKK IFSPRGVYYE KV

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL35043.1.
PIR	B48518. B81366.
RefSeq	YP_002344321.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q0P9X6. 2 interactions.
Genome annotation databases
GeneID	905222.
GenomeReviews	Gene locus Cj0923c in contig AL111168_GR.
KEGG	cje:Cj0923c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0P9X6.
OMA	Q0P9X6. KVLNQMA.
Enzyme and pathway databases
BRENDA	2.1.1.80. 255835.
Family and domain databases
InterPro	IPR000780. CheR_MeTrfase. [Graphical view]
Pfam	PF01739. CheR. 1 hit. PF03705. CheR_N. 1 hit. [Graphical view]
PRINTS	PR00996. CHERMTFRASE.
SMART	SM00138. MeTrc. 1 hit. [Graphical view]
PROSITE	PS50123. CHER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CHER_CAMJE

Accession

Primary (citable) accession number: Q0P9X6
Secondary accession number(s): P45676, Q9PP10

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2007
Last sequence update:	September 19, 2006
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)