Reviewed, UniProtKB/Swiss-Prot Q0P7V6 (RECA_CAMJE)

Names and origin

Protein names

Recommended name:
    Protein recA
Alternative name(s):
    Recombinase A

Gene names

Name:	recA
Ordered Locus Names:	Cj1673c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with lexA causing its activation and leading to its autocatalytic cleavage By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the recA family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA-dependent ATPase activity Inferred from electronic annotation. Source: HAMAP damaged DNA binding Inferred from electronic annotation. Source: HAMAP protein binding Inferred from physical interaction. Source: IntAct single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
fliY	Q0PC74	1	EBI-1194740,EBI-1191111

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Protein recA HAMAP MF_00268		PRO_0000122677
Regions
	Nucleotide binding	65 – 72	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0P7V6-1 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: B5E7FE7FAF424598	FASTA	343	37,049
	10 20 30 40 50 60 MDDNKRKSLD AALKSLDKTF GKGTILRLGD KEVEQIDSIG TGSVGLDLAL GIGGVPKGRI 70 80 90 100 110 120 IEIYGPESSG KTTLTLHIIA ECQKAGGVCA FIDAEHALDV KYAKNLGVNT DDLYVSQPDF 130 140 150 160 170 180 GEQALEIVET IARSGAVDLI VVDSVAALTP KAEIEGDMGD QHVGLQARLM SQALRKLTGI 190 200 210 220 230 240 VHKMNTTVIF INQIRMKIGA MGYGTPETTT GGNALKFYAS VRLDVRKVAT LKQNEEPIGN 250 260 270 280 290 300 RVKVKVVKNK VAPPFRQAEF DVMFGEGLSR EGELIDYGVK LDIVDKSGAW FSYKDKKLGQ 310 320 330 340 GRENSKAFLK ENPEIADEIT KAIQNSMGIE GMISGSEDDE GEE

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL35769.1.
PIR	F81264.
RefSeq	YP_002345041.1.
3D structure databases
HSSP	HSSP built from PDB template 1MO3 based on UniProtKB P26345.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q0P7V6. 14 interactions.
Genome annotation databases
GeneID	905948.
GenomeReviews	Gene locus Cj1673c in contig AL111168_GR.
KEGG	cje:Cj1673c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0P7V6.
OMA	Q0P7V6. GRDNTIT.
Family and domain databases
HAMAP	MF_00268. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR013765. RecA. IPR001553. RecA_bac. [Graphical view]
PANTHER	PTHR22942:SF1. RecA. 1 hit.
Pfam	PF00154. RecA. 1 hit. [Graphical view]
PRINTS	PR00142. RECA.
ProDom	PD000229. RecA. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR02012. tigrfam_recA. 1 hit.
PROSITE	PS00321. RECA_1. 1 hit. PS50162. RECA_2. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECA_CAMJE

Accession

Primary (citable) accession number: Q0P7V6
Secondary accession number(s): P42440, Q9PM04

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	September 19, 2006
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)