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Q0P6M2

- Q0P6M2_ECOLX

UniProt

Q0P6M2 - Q0P6M2_ECOLX

Protein

RNA polymerase sigma factor

Gene

rpoE

Organism
Escherichia coli
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (19 Sep 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: InterPro
    3. sigma factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: InterPro
    2. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Sigma factorUniRule annotationSAAS annotation

    Keywords - Biological processi

    Stress responseImported, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase sigma factorUniRule annotation
    Gene namesi
    Name:rpoEImported
    ORF Names:BC97_10805Imported, BC99_0210605Imported, BN17_18601Imported, BU34_22545Imported, BU65_01430Imported, BU66_01490Imported, BU67_03840Imported, BU68_01125Imported, BU69_10490Imported, BU70_20950Imported, CF57_07525Imported, CF58_21975Imported, CF59_21950Imported, CF60_21615Imported, CF61_08210Imported, DA88_11690Imported, DC22_19415Imported, DC24_14495Imported, DH22_1167Imported, DO98_12640Imported, DP79_24870Imported, ECs3439Imported, EH61_21265Imported, EH62_07935Imported, EH63_21810Imported, EH64_22950Imported, EH65_12725Imported, EH66_05500Imported, EP08_03925Imported, LF82_1962Imported, PGD_00662Imported
    OrganismiEscherichia coliImported
    Taxonomic identifieri562 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000010085: Chromosome

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4LUPX-ray1.20A/C3-92[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the sigma-70 factor family. ECF subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000094755.
    KOiK03088.
    OMAiIDNKIQP.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR014284. RNA_pol_sigma-70_dom.
    IPR000838. RNA_pol_sigma70_ECF_CS.
    IPR007627. RNA_pol_sigma70_r2.
    IPR013249. RNA_pol_sigma70_r4_t2.
    IPR014286. RNA_pol_sigma70_RpoE.
    IPR013325. RNA_pol_sigma_r2.
    IPR013324. RNA_pol_sigma_r3_r4.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF04542. Sigma70_r2. 1 hit.
    PF08281. Sigma70_r4_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF88659. SSF88659. 1 hit.
    SSF88946. SSF88946. 1 hit.
    TIGRFAMsiTIGR02939. RpoE_Sigma70. 1 hit.
    TIGR02937. sigma70-ECF. 1 hit.
    PROSITEiPS01063. SIGMA70_ECF. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q0P6M2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEQLTDQVL VERVQKGDQK AFNLLVVRYQ HKVASLVSRY VPSGDVPDVV    50
    QEAFIKAYRA LDSFRGDSAF YTWLYRIAVN TAKNYLVAQG RRPPSSDVDA 100
    IEAENFESGG ALKEISNPEN LMLSEELRQI VFRTIESLPE DLRMAITLRE 150
    LDGLSYEEIA AIMDCPVGTV RSRIFRAREA IDNKVQPLIR R 191
    Length:191
    Mass (Da):21,696
    Last modified:September 19, 2006 - v1
    Checksum:iC71EEF5939C3611E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY616598 Genomic DNA. Translation: AAZ80065.1.
    EU897165 Genomic DNA. Translation: ACI79721.1.
    EU897166 Genomic DNA. Translation: ACI79722.1.
    EU897167 Genomic DNA. Translation: ACI79723.1.
    EU897168 Genomic DNA. Translation: ACI79724.1.
    EU897169 Genomic DNA. Translation: ACI79725.1.
    CP007265 Genomic DNA. Translation: AHM31215.1.
    CP007390 Genomic DNA. Translation: AHM33558.1.
    CP007391 Genomic DNA. Translation: AHM38155.1.
    CP007392 Genomic DNA. Translation: AHM44815.1.
    CP007393 Genomic DNA. Translation: AHM49423.1.
    CP007394 Genomic DNA. Translation: AHM53873.1.
    CU651637 Genomic DNA. Translation: CAP77019.1.
    HE964769 Genomic DNA. Translation: CCJ45076.1.
    CCCP010000007 Genomic DNA. Translation: CDP70404.1.
    HG976952 Genomic DNA. Translation: CDU37595.1.
    JFFO01000084 Genomic DNA. Translation: EYB38972.1.
    JFFN01000050 Genomic DNA. Translation: EYB46073.1.
    JFFJ01000010 Genomic DNA. Translation: EYB55195.1.
    JFFM01000011 Genomic DNA. Translation: EYB55225.1.
    JFFK01000019 Genomic DNA. Translation: EYB58419.1.
    JFFL01000130 Genomic DNA. Translation: EYB59905.1.
    JEND01000039 Genomic DNA. Translation: KAJ40966.1.
    JJNV01000010 Genomic DNA. Translation: KCW96830.1.
    JHEW01000028 Genomic DNA. Translation: KDM72317.1.
    JHEZ01000024 Genomic DNA. Translation: KDM79683.1.
    JHEX01000034 Genomic DNA. Translation: KDM85972.1.
    JMKH01000021 Genomic DNA. Translation: KDN07943.1.
    JJNT01000026 Genomic DNA. Translation: KDO89837.1.
    JNBX01000105 Genomic DNA. Translation: KDP16542.1.
    JMIZ01000006 Genomic DNA. Translation: KEO97555.1.
    JMJA01000002 Genomic DNA. Translation: KEO99995.1.
    JMJB01000001 Genomic DNA. Translation: KEP06404.1.
    JMJD01000003 Genomic DNA. Translation: KEP09680.1.
    JMJC01000003 Genomic DNA. Translation: KEP17933.1.
    JMJE01000008 Genomic DNA. Translation: KEP20641.1.
    JENE02000001 Genomic DNA. Translation: KEP82556.1.
    RefSeqiYP_002557412.1. NC_011993.1.

    Genome annotation databases

    EnsemblBacteriaiCAP77019; CAP77019; LF82_1962.
    GeneIDi7394209.
    KEGGielf:LF82_1962.
    PATRICi48655060. VBIEscCol74806_2570.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY616598 Genomic DNA. Translation: AAZ80065.1 .
    EU897165 Genomic DNA. Translation: ACI79721.1 .
    EU897166 Genomic DNA. Translation: ACI79722.1 .
    EU897167 Genomic DNA. Translation: ACI79723.1 .
    EU897168 Genomic DNA. Translation: ACI79724.1 .
    EU897169 Genomic DNA. Translation: ACI79725.1 .
    CP007265 Genomic DNA. Translation: AHM31215.1 .
    CP007390 Genomic DNA. Translation: AHM33558.1 .
    CP007391 Genomic DNA. Translation: AHM38155.1 .
    CP007392 Genomic DNA. Translation: AHM44815.1 .
    CP007393 Genomic DNA. Translation: AHM49423.1 .
    CP007394 Genomic DNA. Translation: AHM53873.1 .
    CU651637 Genomic DNA. Translation: CAP77019.1 .
    HE964769 Genomic DNA. Translation: CCJ45076.1 .
    CCCP010000007 Genomic DNA. Translation: CDP70404.1 .
    HG976952 Genomic DNA. Translation: CDU37595.1 .
    JFFO01000084 Genomic DNA. Translation: EYB38972.1 .
    JFFN01000050 Genomic DNA. Translation: EYB46073.1 .
    JFFJ01000010 Genomic DNA. Translation: EYB55195.1 .
    JFFM01000011 Genomic DNA. Translation: EYB55225.1 .
    JFFK01000019 Genomic DNA. Translation: EYB58419.1 .
    JFFL01000130 Genomic DNA. Translation: EYB59905.1 .
    JEND01000039 Genomic DNA. Translation: KAJ40966.1 .
    JJNV01000010 Genomic DNA. Translation: KCW96830.1 .
    JHEW01000028 Genomic DNA. Translation: KDM72317.1 .
    JHEZ01000024 Genomic DNA. Translation: KDM79683.1 .
    JHEX01000034 Genomic DNA. Translation: KDM85972.1 .
    JMKH01000021 Genomic DNA. Translation: KDN07943.1 .
    JJNT01000026 Genomic DNA. Translation: KDO89837.1 .
    JNBX01000105 Genomic DNA. Translation: KDP16542.1 .
    JMIZ01000006 Genomic DNA. Translation: KEO97555.1 .
    JMJA01000002 Genomic DNA. Translation: KEO99995.1 .
    JMJB01000001 Genomic DNA. Translation: KEP06404.1 .
    JMJD01000003 Genomic DNA. Translation: KEP09680.1 .
    JMJC01000003 Genomic DNA. Translation: KEP17933.1 .
    JMJE01000008 Genomic DNA. Translation: KEP20641.1 .
    JENE02000001 Genomic DNA. Translation: KEP82556.1 .
    RefSeqi YP_002557412.1. NC_011993.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4LUP X-ray 1.20 A/C 3-92 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAP77019 ; CAP77019 ; LF82_1962 .
    GeneIDi 7394209.
    KEGGi elf:LF82_1962.
    PATRICi 48655060. VBIEscCol74806_2570.

    Phylogenomic databases

    HOGENOMi HOG000094755.
    KOi K03088.
    OMAi IDNKIQP.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR014284. RNA_pol_sigma-70_dom.
    IPR000838. RNA_pol_sigma70_ECF_CS.
    IPR007627. RNA_pol_sigma70_r2.
    IPR013249. RNA_pol_sigma70_r4_t2.
    IPR014286. RNA_pol_sigma70_RpoE.
    IPR013325. RNA_pol_sigma_r2.
    IPR013324. RNA_pol_sigma_r3_r4.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF04542. Sigma70_r2. 1 hit.
    PF08281. Sigma70_r4_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF88659. SSF88659. 1 hit.
    SSF88946. SSF88946. 1 hit.
    TIGRFAMsi TIGR02939. RpoE_Sigma70. 1 hit.
    TIGR02937. sigma70-ECF. 1 hit.
    PROSITEi PS01063. SIGMA70_ECF. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complex mutation pattern in the design of a protoplast type L-form Escherichia coli."
      Siddiqui R.A., Heinze I., Platzer M.
      Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LW1655F+Imported.
    2. "A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis."
      Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I.
      Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 493/89Imported, 86-24Imported, 87-14Imported, TB182AImported and TW14359Imported.
    3. "Complete genome sequence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease."
      Peyretaillade E., Claret L., Bonnet R., Dossat C., Barbe V., Vacherie B., Segurens B., Peyret P., Darfeuille-Michaud A.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LF82Imported.
    4. "Complete genome sequence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease."
      Peyretaillade E., Claret L., Bonnet R., Dossat C., Barbe V., Vacherie B., Segurens B., Peyret P., Darfeuille-Michaud A.
      Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LF82 / AIECImported.
    5. Genoscope - CEA
      Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LF82Imported.
    6. "Identification of avian pathogenic Escherichia coli serogroup O78 genes associated with pathogenesis in poultry."
      Dziva F., Hauser H., Connor T., Van Diemen P.M., Prescott G., Langridge G.C., Eckert S., Chaudhuri R.R., Ewers C., Mellata M., Curtiss III R., Dougan G., Wieler L., Thomson N.R., Pickard D.J., Stevens M.P.
      Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. Aslett M.
      Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: IMT2125Imported.
    8. "Sequencing and functional annotation of avian pathogenic Escherichia coli serogroup O78 strains reveal the evolution of E. coli lineages pathogenic for poultry via distinct mechanisms."
      Dziva F., Hauser H., Connor T.R., van Diemen P.M., Prescott G., Langridge G.C., Eckert S., Chaudhuri R.R., Ewers C., Mellata M., Mukhopadhyay S., Curtiss R., Dougan G., Wieler L.H., Thomson N.R., Pickard D.J., Stevens M.P.
      Infect. Immun. 81:838-849(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: IMT2125Imported.
    9. "Complete Genome Sequences of Nitrofurantoin-Sensitive and -Resistant Escherichia coli ST540 and ST2747 Strains."
      Xavier B.B., Vervoort J., Stewardson A., Adriaenssens N., Coenen S., Harbarth S., Goossens H., Malhotra-Kumar S.
      Genome Announc. 2:e00239-14(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ST2747Imported and ST540Imported.
    10. "Structural basis for -10 promoter element melting by environmentally induced sigma factors."
      Campagne S., Marsh M.E., Capitani G., Vorholt J.A., Allain F.H.
      Nat. Struct. Mol. Biol. 21:269-276(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.20 ANGSTROMS) OF 3-92.
    11. "Draft Genome Sequence of Escherichia coli str UCD_JA03."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA03Imported.
    12. "Draft Genome Sequence of Escherichia coli str UCD_JA17."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA17Imported.
    13. "Draft Genome Sequence of Escherichia coli str UCD_JA23."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA23Imported.
    14. "Draft Genome Sequence of Escherichia coli str UCD_JA62."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA62Imported.
    15. "Draft Genome Sequence of Escherichia coli str UCD_JA65."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA65Imported.
    16. "Draft Genome Sequence of Escherichia coli str UCD_JA69."
      Coil D., Jospin G., Adams J., Eisen J.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA69Imported.
    17. Britto Xavier B.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ST2747Imported and ST540Imported.
    18. Lai Y.H.
      Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 455Imported.
    19. "Escherichia coli non-O157 genome sequencing."
      Leonard S.R., Lacher D.W.
      Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 97-3250Imported, MI10-01Imported and PMK-5Imported.
    20. "Genome sequence of four bovine mastitis-causing Escherichia coli strains."
      Kempf F., Loux V., Germon P.
      Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: D6-117_07.11Imported.
    21. "A draft genome of Escherichia coli 2009-46."
      Darling A.E., Roy Chowdhury P., Santos J., Worden P., Djordjevic S.P.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 2009-46Imported.
    22. "Draft Genome Sequence of blaNDM-1 positive Escherichia coli O25b-ST131 clone isolated from an environmental sample."
      Kutumbaka K., Han S., Mategko J., Nadala C., Buser G.L., Cassidy M.P., Beldavs Z.G., Weissman S.J., Morey K.E., Vega R., Samadpour M.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: O25b-ST131Imported.
    23. "Escherichia coli UCD_JA03_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA03_pbImported.
    24. "Escherichia coli UCD_JA17_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA17_pbImported.
    25. "Escherichia coli UCD_JA23_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA23_pbImported.
    26. "Escherichia coli UCD_JA62_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA62_pbImported.
    27. "Escherichia coli UCD_JA65_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA65_pbImported.
    28. "Escherichia coli UCD_JA69_pb."
      Coil D.A., Jospin G., Eisen J.A., Adams J.
      Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: UCD_JA69_pbImported.
    29. "Genome Sequence of Enterotoxigenic Escherichia coli Strain W25K."
      Ren W., Liu G., Chen S., Li T., Kong X., Yin Y., Hardwidge P.R.
      Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: W25KImported.
    30. "Genome sequence of four bovine mastitis-causing Escherichia coli strains."
      Kempf F., Loux V., Germon P.
      Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: D6-117_07.11Imported.
    31. "Genome Sequence of Multi-Drug Resistant Escherichia coli ST 131 Causing Neonatal Early-Onset Sepsis."
      Chavez-Bueno S., Day M., Inimary T., Akins D., Dyer D.
      Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SCB34Imported.
    32. Lai Y.H.
      Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 455LImported.

    Entry informationi

    Entry nameiQ0P6M2_ECOLX
    AccessioniPrimary (citable) accession number: Q0P6M2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 19, 2006
    Last sequence update: September 19, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3