Q0P5N6 (ARL16_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ADP-ribosylation factor-like protein 16

Gene names

Name:

ARL16

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the small GTPase superfamily. Arf family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Ligand	GTP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 197	197	ADP-ribosylation factor-like protein 16		PRO_0000264630
Regions
	Nucleotide binding	30 – 37	8	GTP By similarity
	Nucleotide binding	82 – 86	5	GTP By similarity
	Nucleotide binding	139 – 142	4	GTP By similarity
Natural variations
	Natural variant	10	1	S → R. Corresponds to variant rs8066889 [ dbSNP | Ensembl ].		VAR_059129

Sequences

	Sequence		Length	Mass (Da)
	Q0P5N6 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: 678AE0CFE6159E7F	FASTA	197	20,936
	10 20 30 40 50 60 MRVAGGRALS RGAELRVPGG AKHGMCLLLG ATGVGKTLLV KRLQEVSSRD GKGDLGEPPP 70 80 90 100 110 120 TRPTVGTNLT DIVAQRKITI RELGGCMGPI WSSYYGNCRS LLFVMDASDP TQLSASCVQL 130 140 150 160 170 180 LGLLSAEQLA EASVLILFNK IDLPCYMSTE EMKSLIRLPD IIACAKQNIT TAEISAREGT 190 GLAGVLAWLQ ATHRAND

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC105078 mRNA. Translation: AAI05079.1. BC105076 mRNA. Translation: AAI05077.1.
IPI	IPI00242972.
RefSeq	NP_001035114.1. NM_001040025.1.
UniGene	Hs.658789.
3D structure databases
ProteinModelPortal	Q0P5N6.
SMR	Q0P5N6. Positions 20-196.
ModBase	Search...
Polymorphism databases
DMDM	119361248.
Proteomic databases
PRIDE	Q0P5N6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000397498; ENSP00000380635; ENSG00000214087.
GeneID	339231.
KEGG	hsa:339231.
UCSC	uc002kbf.1. human.
Organism-specific databases
CTD	339231.
GeneCards	GC17M079649.
HGNC	HGNC:27902. ARL16.
HPA	HPA043711.
neXtProt	NX_Q0P5N6.
PharmGKB	PA142672583.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00600000084556.
HOGENOM	HBG446218.
HOVERGEN	HBG104241.
InParanoid	Q0P5N6.
OMA	ELGGCMG.
OrthoDB	EOG42RD8S.
PhylomeDB	Q0P5N6.
Gene expression databases
ArrayExpress	Q0P5N6.
Bgee	Q0P5N6.
CleanEx	HS_ARL16.
Genevestigator	Q0P5N6.
Family and domain databases
InterPro	IPR024156. Small_GTPase_ARF. IPR006689. Small_GTPase_ARF/SAR. [Graphical view]
PANTHER	PTHR11711. ARF/SAR. 1 hit.
Pfam	PF00025. Arf. 1 hit. [Graphical view]
PROSITE	PS51417. ARF. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	97302.

Entry information

Entry name

ARL16_HUMAN

Accession

Primary (citable) accession number: Q0P5N6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	September 19, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.