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Protein
Submitted name:

WW domain-containing oxidoreductase

Gene

WWOX

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-1251985. Nuclear signaling by ERBB4.
R-BTA-8866904. Negative regulation of activity of TFAP2 (AP-2) family transcription factors.
R-BTA-8866907. Activation of the TFAP2 (AP-2) family of transcription factors.

Names & Taxonomyi

Protein namesi
Submitted name:
WW domain-containing oxidoreductaseImported
Gene namesi
Name:WWOXImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000015894.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000032547.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 49WWInterPro annotationAdd BLAST34
Domaini57 – 90WWInterPro annotationAdd BLAST34

Phylogenomic databases

eggNOGiKOG1208. Eukaryota.
COG1028. LUCA.
COG5021. LUCA.
GeneTreeiENSGT00760000119068.
HOVERGENiHBG078800.
KOiK19329.
OMAiAATSIYC.
OrthoDBiEOG091G0EI5.
TreeFamiTF105428.

Family and domain databases

CDDicd00201. WW. 2 hits.
InterProiView protein in InterPro
IPR036291. NAD(P)-bd_dom_sf.
IPR002347. SDR_fam.
IPR001202. WW_dom.
IPR036020. WW_dom_sf.
PfamiView protein in Pfam
PF00106. adh_short. 1 hit.
PF00397. WW. 2 hits.
PRINTSiPR00081. GDHRDH.
SMARTiView protein in SMART
SM00456. WW. 2 hits.
SUPFAMiSSF51045. SSF51045. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS01159. WW_DOMAIN_1. 2 hits.
PS50020. WW_DOMAIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q0P5N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALRYAGLD DTDSEDELPP GWEQRTTKDG WVYYANHTEE KTQWEHPKTG
60 70 80 90 100
KRKRIAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK
110 120 130 140 150
PTTRQRYDGS TTAMEILQGR DLSGKVVVVT GANSGIGFET AKSFALHGAH
160 170 180 190 200
VILACRNMTR ANEAVSRILG EWHKAKVEAM TLDLALLRSV QHFAQAFKAK
210 220 230 240 250
NVSLHVLVCN AAVFGLPWTL TKDGLETTFQ VNHLGHFYLV QLLQDVLCRS
260 270 280 290 300
APARVVVVSS ESHRFTDIND SSGKLDFSRL SPSKNDYWAM LAYNRSKLCN
310 320 330 340 350
ILFSNELHRR LSPRGVTSNA VHPGNMMYSA LHRGWWVYTL LFTLARPFTK
360 370 380 390 400
SMQQGAATTV YCAVAPELEG LGGMYFNSCC RCLPSAEAQS EDSARALWAL
410
SERLLQGVPG GPPS
Length:414
Mass (Da):46,191
Last modified:September 19, 2006 - v1
Checksum:iFDEE208DC9E8C103
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02046067 Genomic DNA. No translation available.
DAAA02046068 Genomic DNA. No translation available.
DAAA02046069 Genomic DNA. No translation available.
DAAA02046070 Genomic DNA. No translation available.
DAAA02046071 Genomic DNA. No translation available.
DAAA02046072 Genomic DNA. No translation available.
DAAA02046073 Genomic DNA. No translation available.
DAAA02046074 Genomic DNA. No translation available.
DAAA02046075 Genomic DNA. No translation available.
DAAA02046076 Genomic DNA. No translation available.
BC119823 mRNA. Translation: AAI19824.1.
FJ978047 mRNA. Translation: ADC84386.1.
RefSeqiNP_001071560.1. NM_001078092.1.
UniGeneiBt.104291.
Bt.88210.

Genome annotation databases

EnsembliENSBTAT00000032617; ENSBTAP00000032547; ENSBTAG00000015894.
GeneIDi618792.
KEGGibta:618792.

Similar proteinsi

Entry informationi

Entry nameiQ0P5N4_BOVIN
AccessioniPrimary (citable) accession number: Q0P5N4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: October 25, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported