SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0P5H7

- SYRM_BOVIN

UniProt

Q0P5H7 - SYRM_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable arginine--tRNA ligase, mitochondrial

Gene
RARS2, RARSL
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_209854. Mitochondrial tRNA aminoacylation.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable arginine--tRNA ligase, mitochondrial (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:RARS2
Synonyms:RARSL
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 9

Subcellular locationi

Mitochondrion matrix By similarity

GO - Cellular componenti

  1. mitochondrial matrix Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1616Mitochondrion Reviewed predictionAdd
BLAST
Chaini17 – 578562Probable arginine--tRNA ligase, mitochondrialPRO_0000284070Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei568 – 5681N6-acetyllysine By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ0P5H7.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052997.

Structurei

3D structure databases

ProteinModelPortaliQ0P5H7.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi133 – 14412"HIGH" regionAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0018.
GeneTreeiENSGT00530000063407.
HOGENOMiHOG000247211.
HOVERGENiHBG057355.
KOiK01887.
OMAiELGDMQA.
OrthoDBiEOG7DNNTT.
TreeFamiTF300888.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0P5H7-1 [UniParc]FASTAAdd to Basket

« Hide

MACGFRRSIA SQLSRVLDLP PENLIKSISA VPISRKEEVA DFQLSVDSLL    50
ENNNDHSRPD IQIQAMRLAE KLKCDTVVSE ISTGQGTVNF KINRELLTKT 100
VLQQVIEDGS KYGLKSELFS GLPKKRIVVE FSSPNVAKKF HVGHLRSTII 150
GNFIANLKEA LGHQVTRINY LGDWGMQFGL LGTGFQLFGY EEKLQSSPLQ 200
HLFEVYVQVN KEAADDKNVA KSAHEFFQRL ELGDMQALAL WQKFRDLSID 250
EYMRIYQRLG VHFDEYSGES FYREKSQEVL KLLDSKGLLQ KTLKGTAVVD 300
LSGNGDPSSV CTVMRSDGTS LYATRDLAAA IDRMEKYNFD KMIYVTDKGQ 350
KKHFQQVFQI LQIMGYDWAE RCQHVPFGVV QGMKTRRGDV TFLEDVLNEI 400
RLRMLQNMAS IKTTKELENP EETAEQVGLA ALIIQDFRGF LLSDYQFSWD 450
RVFQSRGDTG VFLQYTHARL HSLEETFGCG YLNDFNTACL QEPQSVSILQ 500
HLLRFDEVLY RSSQDLQPRH IVSYLLTLSH LAAVAHRTLH VRNSPPEVAG 550
ARLHLFRAVR SVLANGMKLL GITPVCRM 578
Length:578
Mass (Da):65,631
Last modified:September 19, 2006 - v1
Checksum:i1CFCBDCA6492CB42
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC120020 mRNA. Translation: AAI20021.1.
RefSeqiNP_001069346.1. NM_001075878.1.
UniGeneiBt.16559.

Genome annotation databases

EnsembliENSBTAT00000022568; ENSBTAP00000022568; ENSBTAG00000016967.
GeneIDi525894.
KEGGibta:525894.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC120020 mRNA. Translation: AAI20021.1 .
RefSeqi NP_001069346.1. NM_001075878.1.
UniGenei Bt.16559.

3D structure databases

ProteinModelPortali Q0P5H7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000052997.

Proteomic databases

PRIDEi Q0P5H7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000022568 ; ENSBTAP00000022568 ; ENSBTAG00000016967 .
GeneIDi 525894.
KEGGi bta:525894.

Organism-specific databases

CTDi 57038.

Phylogenomic databases

eggNOGi COG0018.
GeneTreei ENSGT00530000063407.
HOGENOMi HOG000247211.
HOVERGENi HBG057355.
KOi K01887.
OMAi ELGDMQA.
OrthoDBi EOG7DNNTT.
TreeFami TF300888.

Enzyme and pathway databases

Reactomei REACT_209854. Mitochondrial tRNA aminoacylation.

Miscellaneous databases

NextBioi 20874255.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Fetal cerebellum.

Entry informationi

Entry nameiSYRM_BOVIN
AccessioniPrimary (citable) accession number: Q0P5H7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: September 19, 2006
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi