Q0P5A5 (CKS1_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-dependent kinases regulatory subunit 1
Short name=CKS-1

Gene names

Name:	CKS1B
Synonyms:	CKS1

Organism

Bos taurus (Bovine) [Reference proteome]

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	79 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function By similarity.
Subunit structure	Forms a homohexamer that can probably bind six kinase subunits By similarity.
Sequence similarities	Belongs to the CKS family.

Ontologies

Keywords
Biological process	Cell cycle Cell division
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 79	79	Cyclin-dependent kinases regulatory subunit 1		PRO_0000260446

Sequences

	Sequence		Length	Mass (Da)
	Q0P5A5 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: E64207B140FA38D5	FASTA	79	9,660
	10 20 30 40 50 60 MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ SQGWVHYMIH 70 EPEPHILLFR RPLPKKPKK

References

[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Hereford. Tissue: Placenta.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC120301 mRNA. Translation: AAI20302.1.
IPI	IPI00696609.
RefSeq	NP_001106782.1. NM_001113311.1.
UniGene	Bt.20570.
3D structure databases
ProteinModelPortal	Q0P5A5.
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000033878.
Proteomic databases
PRIDE	Q0P5A5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000033975; ENSBTAP00000033878; ENSBTAG00000024476.
GeneID	615827.
KEGG	bta:615827.
Organism-specific databases
CTD	1163.
Phylogenomic databases
eggNOG	NOG272189.
GeneTree	ENSGT00390000011006.
HOVERGEN	HBG003626.
InParanoid	Q0P5A5.
KO	K02219.
OMA	QPEPHIL.
OrthoDB	EOG4JM7RB.
Family and domain databases
Gene3D	3.30.170.10. 1 hit.
InterPro	IPR000789. Cyclin-dep_kinase_reg-sub. [Graphical view]
Pfam	PF01111. CKS. 1 hit. [Graphical view]
PRINTS	PR00296. CYCLINKINASE.
SMART	SM01084. CKS. 1 hit. [Graphical view]
SUPFAM	SSF55637. Cyc_dep_kin_rsub. 1 hit.
PROSITE	PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20899807.

Entry information

Entry name

CKS1_BOVIN

Accession

Primary (citable) accession number: Q0P5A5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	September 19, 2006
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program