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Q0P5A5

- CKS1_BOVIN

UniProt

Q0P5A5 - CKS1_BOVIN

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Protein

Cyclin-dependent kinases regulatory subunit 1

Gene

CKS1B

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.By similarity

GO - Molecular functioni

  1. cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunit 1
Short name:
CKS-1
Gene namesi
Name:CKS1B
Synonyms:CKS1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 7978Cyclin-dependent kinases regulatory subunit 1PRO_0000260446Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ0P5A5.

Interactioni

Subunit structurei

Forms a homohexamer that can probably bind six kinase subunits.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000033878.

Structurei

3D structure databases

ProteinModelPortaliQ0P5A5.
SMRiQ0P5A5. Positions 5-74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.Curated

Phylogenomic databases

eggNOGiNOG272189.
GeneTreeiENSGT00390000011006.
HOVERGENiHBG003626.
InParanoidiQ0P5A5.
KOiK02219.
OMAiRGWIHYM.
OrthoDBiEOG735413.
TreeFamiTF101142.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0P5A5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ
60 70
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Length:79
Mass (Da):9,660
Last modified:September 19, 2006 - v1
Checksum:iE64207B140FA38D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120301 mRNA. Translation: AAI20302.1.
RefSeqiNP_001106782.1. NM_001113311.1.
UniGeneiBt.20570.

Genome annotation databases

EnsembliENSBTAT00000033975; ENSBTAP00000033878; ENSBTAG00000024476.
GeneIDi615827.
KEGGibta:615827.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120301 mRNA. Translation: AAI20302.1 .
RefSeqi NP_001106782.1. NM_001113311.1.
UniGenei Bt.20570.

3D structure databases

ProteinModelPortali Q0P5A5.
SMRi Q0P5A5. Positions 5-74.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000033878.

Proteomic databases

PRIDEi Q0P5A5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000033975 ; ENSBTAP00000033878 ; ENSBTAG00000024476 .
GeneIDi 615827.
KEGGi bta:615827.

Organism-specific databases

CTDi 1163.

Phylogenomic databases

eggNOGi NOG272189.
GeneTreei ENSGT00390000011006.
HOVERGENi HBG003626.
InParanoidi Q0P5A5.
KOi K02219.
OMAi RGWIHYM.
OrthoDBi EOG735413.
TreeFami TF101142.

Miscellaneous databases

NextBioi 20899807.

Family and domain databases

Gene3Di 3.30.170.10. 1 hit.
InterProi IPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view ]
Pfami PF01111. CKS. 1 hit.
[Graphical view ]
PRINTSi PR00296. CYCLINKINASE.
SMARTi SM01084. CKS. 1 hit.
[Graphical view ]
SUPFAMi SSF55637. SSF55637. 1 hit.
PROSITEi PS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Placenta.

Entry informationi

Entry nameiCKS1_BOVIN
AccessioniPrimary (citable) accession number: Q0P5A5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 19, 2006
Last modified: November 26, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3