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Protein

Lipase maturation factor 2

Gene

lmf2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the maturation of specific proteins in the endoplasmic reticulum.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Lipase maturation factor 2
Gene namesi
Name:lmf2
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-974438. lmf2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Transmembranei220 – 240HelicalSequence analysisAdd BLAST21
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21
Transmembranei306 – 326HelicalSequence analysisAdd BLAST21
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei398 – 418HelicalSequence analysisAdd BLAST21
Transmembranei634 – 654HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003245151 – 707Lipase maturation factor 2Add BLAST707

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi483N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ0P4Y8.

Structurei

3D structure databases

SMRiQ0P4Y8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lipase maturation factor family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IFKQ. Eukaryota.
ENOG410XPYW. LUCA.
HOGENOMiHOG000019333.
HOVERGENiHBG108090.
InParanoidiQ0P4Y8.

Family and domain databases

InterProiView protein in InterPro
IPR009613. LMF.
PfamiView protein in Pfam
PF06762. LMF1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0P4Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEQRLARSS FLWGLSGIYL VAFVSLYAQI PGLYGREGIL PAWKMMRFTG
60 70 80 90 100
KGFWEQLKDS PSLLWFGPRL GLDTEMTMEM ICLLGALLSL GALLFSFLRD
110 120 130 140 150
SLVFLLLWIF YLSLYQVGQV FLYFQWDSLL LETGFLAVLV APVHALRWKT
160 170 180 190 200
SVWSSHDGVT FWLTRWLLFR LMFASGIVKL TSRCPTWWGL TALTYHYETQ
210 220 230 240 250
CIPNPAAWFA HQLPVWFQKF SVVATYFIEI GVPLLFFLPF RRLRLFSFYS
260 270 280 290 300
QVVLQILIIM TGNYNFFNLL TVVLCCSLLD DQHITFFQRH KKPQHKGGRV
310 320 330 340 350
TSAFSLYSLI SLLDVPIFGL LVFWTVKYFD LQINWEKHSV ESRTAFTYHD
360 370 380 390 400
FQQWLRTITF PTIWIAAASL GWEILKGMYR SASVRGIFWK LWSTLQWVIF
410 420 430 440 450
SCAAVAMFTI SLVPYTYIDF ESNGHLWPEV HRMFNAVDRY QLVNSYGLFR
460 470 480 490 500
RMTGVGGRPE VIVEGSYDRE TWTEIEFMYK PGNISTTPSV IIPHQPRLDW
510 520 530 540 550
QMWFAALAHN SHSPWFASFV YRLLQGNKDV IHLVQNDESL YPFHAYPPTY
560 570 580 590 600
IRAQLYKYWF TEVDQSGQMP KSWWRRRHVE EFFPAVFLGD PFLDNLLTQH
610 620 630 640 650
GLKDKPPARR SLDAPIPSAL RLIRAFLHPL PAPLLLHSFI FGIFTIYFLQ
660 670 680 690 700
AMFGGVSKPG VAKQRHSKPP NEKKKQKSNS GQGESAAAKS SGHGADTVRR

NKKNEKS
Length:707
Mass (Da):81,968
Last modified:September 19, 2006 - v1
Checksum:i99EACFCAA84524B8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80M → L in AAH92370 (Ref. 1) Curated1
Sequence conflicti143V → L in AAH92370 (Ref. 1) Curated1
Sequence conflicti148W → C in AAH92370 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092370 mRNA. Translation: AAH92370.1.
BC121839 mRNA. Translation: AAI21840.1.
RefSeqiNP_001072170.1. NM_001078702.1.
UniGeneiStr.17802.

Genome annotation databases

GeneIDi594899.
KEGGixtr:594899.

Similar proteinsi

Entry informationi

Entry nameiLMF2_XENTR
AccessioniPrimary (citable) accession number: Q0P4Y8
Secondary accession number(s): Q569N7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 19, 2006
Last modified: July 5, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families