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Protein

Mitochondrial coenzyme A transporter SLC25A42

Gene

slc25a42

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial coenzyme A transporter SLC25A42
Alternative name(s):
Solute carrier family 25 member 42
Gene namesi
ORF Names:zgc:153304
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-060825-313. slc25a42.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei35 – 5521Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei91 – 11121Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei137 – 15418Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei191 – 20818Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei232 – 25221Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei295 – 31521Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321Mitochondrial coenzyme A transporter SLC25A42PRO_0000291820Add
BLAST

Proteomic databases

PaxDbiQ0P483.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112426.

Structurei

3D structure databases

ProteinModelPortaliQ0P483.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati33 – 11987Solcar 1Add
BLAST
Repeati131 – 21686Solcar 2Add
BLAST
Repeati226 – 31489Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
HOGENOMiHOG000165726.
HOVERGENiHBG104402.
InParanoidiQ0P483.
KOiK15085.
PhylomeDBiQ0P483.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0P483-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNVVQERQG ALAQGEVLPR PAASQSEGFK QGRSVLNSLV SGAFAGAVAK
60 70 80 90 100
TAVAPLDRTK IIFQVSSNRF SAKEAYRLIY RTYLKDGFFS LWRGNSATMV
110 120 130 140 150
RVIPYAAIQF CAHEQYKGIL GKYYGFQGKA LPPVPRLLAG SLAGTTAAII
160 170 180 190 200
TYPLDMVRAR MAVTPKEMYS NIMDVFVRIS REEGLKTLYR GFTPTILGVV
210 220 230 240 250
PYAGLSFFTY ETLKKTHAEK TGRAHPFPYE RLVFGACAGL IGQSASYPLD
260 270 280 290 300
VVRRRMQTAG VTGHTYSTVL GTMREIVAEE GIVRGLYKGL SMNWVKGPIA
310 320
VGISFMTFDL TQILLRKFQL L
Length:321
Mass (Da):35,336
Last modified:September 19, 2006 - v1
Checksum:i16285B1BADDB42C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC122225 mRNA. Translation: AAI22226.1.
RefSeqiNP_001038918.1. NM_001045453.1.
UniGeneiDr.91774.

Genome annotation databases

GeneIDi751743.
KEGGidre:751743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC122225 mRNA. Translation: AAI22226.1.
RefSeqiNP_001038918.1. NM_001045453.1.
UniGeneiDr.91774.

3D structure databases

ProteinModelPortaliQ0P483.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112426.

Proteomic databases

PaxDbiQ0P483.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi751743.
KEGGidre:751743.

Organism-specific databases

CTDi284439.
ZFINiZDB-GENE-060825-313. slc25a42.

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
HOGENOMiHOG000165726.
HOVERGENiHBG104402.
InParanoidiQ0P483.
KOiK15085.
PhylomeDBiQ0P483.

Miscellaneous databases

PROiQ0P483.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS2542_DANRE
AccessioniPrimary (citable) accession number: Q0P483
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: September 19, 2006
Last modified: July 6, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.