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Protein

NADH dehydrogenase [ubiquinone] 1 subunit C2

Gene

NDUFC2

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 subunit C2
Alternative name(s):
Complex I-B14.5b
Short name:
CI-B14.5b
NADH-ubiquinone oxidoreductase subunit B14.5b
Gene namesi
Name:NDUFC2
OrganismiGorilla gorilla gorilla (Western lowland gorilla)
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 75HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002518501 – 119NADH dehydrogenase [ubiquinone] 1 subunit C2Add BLAST119

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000005070.

Structurei

3D structure databases

ProteinModelPortaliQ0MQF8.
SMRiQ0MQF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFC2 subunit family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG001727.
InParanoidiQ0MQF8.
OMAiIVEPFHP.

Family and domain databases

InterProiView protein in InterPro
IPR009423. NADH-UbQ_OxRdtase_b14.5b_su.
PANTHERiPTHR13099. PTHR13099. 1 hit.
PfamiView protein in Pfam
PF06374. NDUF_C2. 1 hit.
PIRSFiPIRSF017834. NADH-UbQ_OxRdtase_b14.5b. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0MQF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIARRNPEPL RFLPDEARSL PPPKLTDPRL LYIGFLGYCS GLIDNLIRRR
60 70 80 90 100
PIATAGLHRQ LLYITAFFFA GYYLVKREDY LYAVRDREMF GYMKLHPEDF
110
PEEDKKTYGE IFEKFHPIR
Length:119
Mass (Da):14,188
Last modified:September 19, 2006 - v1
Checksum:i9A47DEE33DC9244D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ885676 mRNA. Translation: ABH12185.1.
RefSeqiNP_001266623.1. NM_001279694.1.

Genome annotation databases

GeneIDi101142450.

Similar proteinsi

Entry informationi

Entry nameiNDUC2_GORGO
AccessioniPrimary (citable) accession number: Q0MQF8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: September 19, 2006
Last modified: September 27, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families