Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:H16_A0159
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180991 – 595Arginine--tRNA ligaseAdd BLAST595

Proteomic databases

PRIDEiQ0KFB0

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi381666.H16_A0159

Structurei

3D structure databases

ProteinModelPortaliQ0KFB0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 2 hits
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q0KFB0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPVQTSNLA AAFTDAVRAL APADATLPAV TFERPKVAAH GDLACNVAMQ
60 70 80 90 100
VARALKSNPR ELAQRIVDAV QADTRAQGLV QAMEIAGPGF INLRLTPAAK
110 120 130 140 150
ADVLRAVLAE GDHYGARERG VHGQVLVEFV SANPTGPLHV GHGRQAALGD
160 170 180 190 200
ALANLLSWQG WHVHREFYYN DAGVQIQTLA LSVQARARGL KPGDASWPEA
210 220 230 240 250
AYNGDYIADI AADFLAGKTV SASDGEPVTA SGNVEDIDSI RKFAVTYLRN
260 270 280 290 300
EQDIDLQAFG VKFDRYYLES SLYSDGRVEA AVQSLVGKGK TYESEGALWL
310 320 330 340 350
RTTDDGDDKD RVMKKSDGTY TYFVPDVAYH TTKWERGFTK VINVQGSDHH
360 370 380 390 400
GTIARVRAGL QGLDMGIPQG YPDYVLHKMV TVMKNGEEVK ISKRAGSYVT
410 420 430 440 450
VRDLIEWSNG GDETIRGCLD TGVADWPQHF TRGRDAVRFF LLSRKADTEF
460 470 480 490 500
VFDVDLALKQ NDENPVYYVQ YAHARICSIF ESWGGADWEA RLAELAGADL
510 520 530 540 550
SAVTGPEASA QAQALGRRLA EFPDMLSGAA AELAPHAVAF YLRDLAGDFH
560 570 580 590
AFYNADRVLV DDEAVKRARL ALLAATRQVL RNGLAVIGVS APRRM
Length:595
Mass (Da):64,725
Last modified:October 3, 2006 - v1
Checksum:i22595641761F6198
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA Translation: CAJ91311.1
RefSeqiWP_010812880.1, NC_008313.1

Genome annotation databases

EnsemblBacteriaiCAJ91311; CAJ91311; H16_A0159
KEGGireh:H16_A0159

Entry informationi

Entry nameiSYR_CUPNH
AccessioniPrimary (citable) accession number: Q0KFB0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health