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Q0KES8 (Q0KES8_CUPNH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 2 RuleBase RU004024
EC=1.9.3.1 RuleBase RU004024
Gene names
Name:ctaC EMBL CAJ91493.1
Ordered Locus Names:H16_A0342 EMBL CAJ91493.1
OrganismCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) [Complete proteome] [HAMAP] EMBL CAJ91493.1
Taxonomic identifier381666 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus ›

Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) By similarity. RuleBase RU004024

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. RuleBase RU004024

Cofactor

Copper A By similarity. RuleBase RU004024

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 2 family.

Sequences

Sequence LengthMass (Da)Tools
Q0KES8 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 23E3F2EE9FBC8F2E

FASTA42045,456
        10         20         30         40         50         60 
MKMWKKASAV CLAGASLLAS QAASAVSDMP GGPAVRQLNL TEPVTKIAEQ IHWLNWMMLI 

        70         80         90        100        110        120 
MCTVIFVAVF SVMFYSVFKH RKAKGAKPAA FHESITVEVI WTIVPFIIVI AMALPATKTV 

       130        140        150        160        170        180 
VAMKDTTNSD ITIKATGYQW KWGYDYLKGE GEGISFVSTL TTPREQINNE QPKSNTYLME 

       190        200        210        220        230        240 
VDNELVVPVN KKIRIVTTAN DVIHAWMIPA FGVKQDAIPG FVRDTWFKAE KIGVYRGQCA 

       250        260        270        280        290        300 
ELCGKEHAFM PIVVRVVSDA DYTKWVDGKK KELAAKADDP NKTWTLDESK VRGEKVYAAN 

       310        320        330        340        350        360 
CAVCHQPNGK GGGAFPALDG SKLVNGPKAG QMHIMLEGKA AMPSWKQLSD TELAAVMTYT 

       370        380        390        400        410        420 
RNAWSNKTGE VVQPSDFVGA RAGKFPEGGG AAGGAAPKAE AKPADKADKQ ASLAGNRVAG

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References

[1]"Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16."
Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R., Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I., Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.
Nat. Biotechnol. 24:1257-1262(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM260479 Genomic DNA. Translation: CAJ91493.1.
RefSeqYP_724861.1. NC_008313.1.

3D structure databases

ProteinModelPortalQ0KES8.
ModBaseSearch...

Protein-protein interaction databases

STRING381666.H16_A0342.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ91493; CAJ91493; H16_A0342.
GeneID4247233.
KEGGreh:H16_A0342.
PATRIC35230069. VBIRalEut6770_0705.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2010.
HOGENOMHOG000264987.
KOK02275.
OMAWGNNTGD.
ProtClustDBCLSK629573.

Enzyme and pathway databases

BioCycCNEC381666:GJUJ-342-MONOMER.

Family and domain databases

Gene3D1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProIPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR009056. Cyt_c_dom.
IPR014222. Cyt_c_oxidase_su2.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view]
PfamPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
SUPFAMSSF49503. Cupredoxin. 1 hit.
SSF81464. Cyt_c_oxidase_II-like_TM. 1 hit.
SSF46626. Cytochrome_c. 1 hit.
TIGRFAMsTIGR02866. CoxB. 1 hit.
PROSITEPS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
PS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0KES8_CUPNH
AccessionPrimary (citable) accession number: Q0KES8
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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