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Q0KBT2

- LFTR_CUPNH

UniProt

Q0KBT2 - LFTR_CUPNH

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-1400-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:H16_A1403
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 250250Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000304351Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi381666.H16_A1403.

Structurei

3D structure databases

ProteinModelPortaliQ0KBT2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiGAVEIDH.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0KBT2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIAWLDPQDP FPPVDEALGP DSEAPGLLAA SRDLSPQRLL LAYRQGIFPW
60 70 80 90 100
YSSGQPVLWW STDPRMVLAP PALRVSLNLR KTLRRVLRDA DWEIRVDDDF
110 120 130 140 150
LAVMRACATT PRDGQDGTWI TDDIIAAYGT LHRNGMAHSV ESWYRGERVG
160 170 180 190 200
GLYGVALGRM FFGESMFAHR TDASKIALAA LCAFLGNHGV AMIDCQQETD
210 220 230 240 250
HLASLGARPI PRAEFVAHVR AATALPAISP WRFDKSVLER WAGTPAAPAG
Length:250
Mass (Da):27,503
Last modified:October 3, 2006 - v1
Checksum:iC666D4FEECF44BD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ92539.1.
RefSeqiYP_725907.1. NC_008313.1.

Genome annotation databases

EnsemblBacteriaiCAJ92539; CAJ92539; H16_A1403.
GeneIDi4247208.
KEGGireh:H16_A1403.
PATRICi35232269. VBIRalEut6770_1792.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ92539.1 .
RefSeqi YP_725907.1. NC_008313.1.

3D structure databases

ProteinModelPortali Q0KBT2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 381666.H16_A1403.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ92539 ; CAJ92539 ; H16_A1403 .
GeneIDi 4247208.
KEGGi reh:H16_A1403.
PATRICi 35232269. VBIRalEut6770_1792.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi GAVEIDH.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci CNEC381666:GJUJ-1400-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Entry informationi

Entry nameiLFTR_CUPNH
AccessioniPrimary (citable) accession number: Q0KBT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 3, 2006
Last modified: November 26, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3