Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0KA59

- TYPH1_CUPNH

UniProt

Q0KA59 - TYPH1_CUPNH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative thymidine phosphorylase 1

Gene

H16_A2012

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-1980-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase 1UniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPase 1UniRule annotation
Gene namesi
Ordered Locus Names:H16_A2012
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520Putative thymidine phosphorylase 1PRO_0000314708Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi381666.H16_A2012.

Structurei

3D structure databases

ProteinModelPortaliQ0KA59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiMNDASSD.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0KA59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNDASSDPGI PGRPGDVVAA AAPREVGALV FRPLEIDTWQ EHVIYMHPDC
60 70 80 90 100
PVCRAEGFSA QARVRVQIGD RSLIATLTLL GAPLLNTGEA SLSLSAARTL
110 120 130 140 150
SARAGDVVHV THAPALESVR ALRAKIYGCH LDSVQLDGII GDISAGRYAD
160 170 180 190 200
VHIAAFLTAC ADGRMSLRET VDLTRAMVRS GQRLNWDREV VADKHCVGGL
210 220 230 240 250
PGNRTTPVVV AIAAAAGLLL PKTSSRAITS PAGTADTMEA LTRVTLDSTE
260 270 280 290 300
LRRVVEQVGA ALVWGGALSL SPADDVLIRV ERALDIDSDA QLVASILSKK
310 320 330 340 350
IAAGSTHVLI DVPVGPTAKI REDSDLARLD LAMTKVADAF GLKLRILRTD
360 370 380 390 400
GSQPVGRGVG PALEALDVLA VLQCQPTAPA DLRERSLLLA GELLEFCGAI
410 420 430 440 450
PPGQGRLLAG SLLDSGAAWA RFQAICEAQG GLRTPGQAVF RRDVVAARSG
460 470 480 490 500
IVTSVDNRHV ARTAKLAGAP RRQVAGLELH VRAGDEVVAG APLCTLHAQA
510 520
SGELEYAFSY ALAHDPFRIE
Length:520
Mass (Da):54,581
Last modified:October 3, 2006 - v1
Checksum:i4DA9BFC23FD5A27E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ93112.1.
RefSeqiYP_726480.1. NC_008313.1.

Genome annotation databases

EnsemblBacteriaiCAJ93112; CAJ93112; H16_A2012.
GeneIDi4248759.
KEGGireh:H16_A2012.
PATRICi35233535. VBIRalEut6770_2418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ93112.1 .
RefSeqi YP_726480.1. NC_008313.1.

3D structure databases

ProteinModelPortali Q0KA59.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 381666.H16_A2012.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ93112 ; CAJ93112 ; H16_A2012 .
GeneIDi 4248759.
KEGGi reh:H16_A2012.
PATRICi 35233535. VBIRalEut6770_2418.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi MNDASSD.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci CNEC381666:GJUJ-1980-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Entry informationi

Entry nameiTYPH1_CUPNH
AccessioniPrimary (citable) accession number: Q0KA59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: November 26, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3