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Protein

Putative thymidine phosphorylase 1

Gene

H16_A2012

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase 1UniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPase 1UniRule annotation
Gene namesi
Ordered Locus Names:H16_A2012
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000008210 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003147081 – 520Putative thymidine phosphorylase 1Add BLAST520

Proteomic databases

PRIDEiQ0KA59

Interactioni

Protein-protein interaction databases

STRINGi381666.H16_A2012

Structurei

3D structure databases

ProteinModelPortaliQ0KA59
SMRiQ0KA59
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA
HOGENOMiHOG000252767
KOiK00758
OMAiANEIYEC

Family and domain databases

Gene3Di3.40.1030.10, 1 hit
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q0KA59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDASSDPGI PGRPGDVVAA AAPREVGALV FRPLEIDTWQ EHVIYMHPDC
60 70 80 90 100
PVCRAEGFSA QARVRVQIGD RSLIATLTLL GAPLLNTGEA SLSLSAARTL
110 120 130 140 150
SARAGDVVHV THAPALESVR ALRAKIYGCH LDSVQLDGII GDISAGRYAD
160 170 180 190 200
VHIAAFLTAC ADGRMSLRET VDLTRAMVRS GQRLNWDREV VADKHCVGGL
210 220 230 240 250
PGNRTTPVVV AIAAAAGLLL PKTSSRAITS PAGTADTMEA LTRVTLDSTE
260 270 280 290 300
LRRVVEQVGA ALVWGGALSL SPADDVLIRV ERALDIDSDA QLVASILSKK
310 320 330 340 350
IAAGSTHVLI DVPVGPTAKI REDSDLARLD LAMTKVADAF GLKLRILRTD
360 370 380 390 400
GSQPVGRGVG PALEALDVLA VLQCQPTAPA DLRERSLLLA GELLEFCGAI
410 420 430 440 450
PPGQGRLLAG SLLDSGAAWA RFQAICEAQG GLRTPGQAVF RRDVVAARSG
460 470 480 490 500
IVTSVDNRHV ARTAKLAGAP RRQVAGLELH VRAGDEVVAG APLCTLHAQA
510 520
SGELEYAFSY ALAHDPFRIE
Length:520
Mass (Da):54,581
Last modified:October 3, 2006 - v1
Checksum:i4DA9BFC23FD5A27E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA Translation: CAJ93112.1

Genome annotation databases

EnsemblBacteriaiCAJ93112; CAJ93112; H16_A2012
KEGGireh:H16_A2012

Similar proteinsi

Entry informationi

Entry nameiTYPH1_CUPNH
AccessioniPrimary (citable) accession number: Q0KA59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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