Q0K979 (TAL_CUPNH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	H16_A2346

Organism

Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) [Complete proteome] [HAMAP]

Taxonomic identifier

381666 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 318	318	Transaldolase HAMAP MF_00492		PRO_1000014516
Sites
	Active site	126	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0K979 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: B78AD8408248915A	FASTA	318	34,963
	10 20 30 40 50 60 MNQLEQLRQF TTVVADTGDF QLMKQYTPQD ATTNPSLILK AVQKPEYRHL LEKAVQDHHG 70 80 90 100 110 120 NGGVDAVMDE VLIAFGCEIL AIVPGRVSTE VDARLSFDTE ASVAKARHLI QLYEQRGIAR 130 140 150 160 170 180 ERVLIKIAST WEGIRAAEIL QRDGIRCNMT LLFSLVQAVA CAEAGAQLIS PFVGRIFDWY 190 200 210 220 230 240 KKQAGEQWDA AANGGDNDPG VRSVRQIYDY YKKFGYPTEV MGASFRSTTQ ILSLAGCDLL 250 260 270 280 290 300 TISPELLEQL AAGQGPVAHK LSVDQAQAAN IARIAADEPA FRWQLNEDAM ATEKLAEGIR 310 LFAADAVKLE KLIGEIAK

References

[1]

"Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16." Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R., Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I., Gottschalk G., Steinbuechel A., Friedrich B., Bowien B. Nat. Biotechnol. 24:1257-1262(2006) [PubMed: 16964242] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM260479 Genomic DNA. Translation: CAJ93442.1.
RefSeq	YP_726810.1. NC_008313.1.
3D structure databases
ProteinModelPortal	Q0K979.
SMR	Q0K979. Positions 1-315.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0K979.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4246933.
GenomeReviews	Gene locus H16_A2346 in contig AM260479_GR.
KEGG	reh:H16_A2346.
PATRIC	35234213. VBIRalEut6770_2753.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HBG286747.
OMA	GCEILAI.
PhylomeDB	Q0K979.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	REUT381666:H16_A2346-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_CUPNH

Accession

Primary (citable) accession number: Q0K979

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program