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Q0K7M4

- Q0K7M4_CUPNH

UniProt

Q0K7M4 - Q0K7M4_CUPNH

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, H16_A2921
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei215 – 2151 By similarityUniRule annotation
Active sitei662 – 6621 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-2885-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:H16_A2921Imported
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)Imported
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210: Chromosome 1

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi381666.H16_A2921.

Structurei

3D structure databases

ProteinModelPortaliQ0K7M4.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiRERSHNE.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0K7M4-1 [UniParc]FASTAAdd to Basket

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MTQHAARPNG RRTAPAAKDQ SPALGAAQGD ANGASAAEPK RPASRSGTKR     50
SPKPKLSIVS SNGTTIAPTA RRTADKDVPL REDIRFLGRL LGECLREQEG 100
DAAFEVVETI RQTAVRFRRE NDRAAGAELD RLLKRLSRDQ TNQVVRAFSY 150
FSHLANIAED QHHNRRRRVH ALAGSPPQAG SLAHALEAID AAGVTGKQLR 200
KFLDEALIVP VLTAHPTEVQ RKSILDAERE IARLLAERDL PMTARERDHN 250
TAQLRAKVTT LWQTRMLRDS RLTVADEIEN ALSYYRTCFL RGIPQLMSEL 300
EEDIAAVFPT TRKRKGTPGA QPAPLAPFLQ MGSWIGGDRD GNPNVTAETL 350
EHAASQQGQM IIDWYLDEVH ALGAELSMST LMVDASPELL ALAERSPDHS 400
EHRADEPYRR ALIGIYARLA ATSKALTGHA VPRRPVAPAE PYDSAEAFAA 450
DVQVVVDSLR ANHGQALANG RIEALARAIG VFGFHLASVD MRQVSDVHEA 500
VIAELFAAAG IAPDYAALPE ARKLELLLAE LRQPRLLTLP WHEYSEQTRK 550
ELAIFAAARE LRARYGKRIA RNYIISHTET LSDLVEVMLL QKESGMLQGT 600
LGSKTDPARM ELMVIPLFET IEDLRNAAGI MQSLLDLPGF DSVIAHHGVE 650
QEVMLGYSDS NKDGGFLTST WELYKAELEL VQLFEQRQVK LRLFHGRGGT 700
VGRGGGPTYQ AILSQPPGTV NGQIRLTEQG EIINSKFANA EIGRRNLETV 750
VAATLEASLL PQQNAPKDLD MFEAVMQQLS DRAFTAYRDL VYETPGFKDY 800
FFATTPITEI ADLNLGSRPA SRKLMDKKNR RIEDLRAIPW GFSWGQCRLL 850
LPGWYGFGSA VKSLLDTAPD DKARKLAVTT LRRMVKTWPF FSTLLSNMDM 900
VLAKTDLAVA SRYAQLCDDA ALRRTVFNRI SKEWHLTCEM LTLVTGHQER 950
LADNPLLARS IKNRFAYLDP LNHLQVELLK RYRSGKDGDD IRVRRGIHLT 1000
INGVAAGLRN TG 1012
Length:1,012
Mass (Da):112,160
Last modified:October 3, 2006 - v1
Checksum:iD5765D8914ECE8D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM260479 Genomic DNA. Translation: CAJ93997.1.
RefSeqiYP_727365.1. NC_008313.1.

Genome annotation databases

EnsemblBacteriaiCAJ93997; CAJ93997; H16_A2921.
GeneIDi4250259.
KEGGireh:H16_A2921.
PATRICi35235375. VBIRalEut6770_3317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM260479 Genomic DNA. Translation: CAJ93997.1 .
RefSeqi YP_727365.1. NC_008313.1.

3D structure databases

ProteinModelPortali Q0K7M4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 381666.H16_A2921.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ93997 ; CAJ93997 ; H16_A2921 .
GeneIDi 4250259.
KEGGi reh:H16_A2921.
PATRICi 35235375. VBIRalEut6770_3317.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi RERSHNE.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci CNEC381666:GJUJ-2885-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Entry informationi

Entry nameiQ0K7M4_CUPNH
AccessioniPrimary (citable) accession number: Q0K7M4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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