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Q0K3Q9 (Q0K3Q9_CUPNH) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aconitate hydratase 2 PIRNR PIRNR036687

EC=4.2.1.3 PIRNR PIRNR036687
EC=4.2.1.99 PIRNR PIRNR036687
Alternative name(s):
2-methylisocitrate dehydratase PIRNR PIRNR036687
Gene names
Name:acnB EMBL CAJ95365.1
Ordered Locus Names:H16_B0568 EMBL CAJ95365.1
OrganismCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) [Complete proteome] [HAMAP] EMBL CAJ95365.1
Taxonomic identifier381666 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

Protein attributes

Sequence length863 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O. PIRNR PIRNR036687

Citrate = isocitrate. PIRNR PIRNR036687

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2. PIRNR PIRNR036687

Sequence similarities

Belongs to the aconitase/IPM isomerase family. PIRNR PIRNR036687

Sequences

Sequence LengthMass (Da)Tools
Q0K3Q9 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 6624228948299E1E

FASTA86393,126
        10         20         30         40         50         60 
MLENYRAHVA ERAALGIPPL PLTAKQTAEL VELLKNPPAG EEQTLVELIT YRVPAGVDDA 

        70         80         90        100        110        120 
AKVKASYLAA VALGKEKCAL ISRAKATELL GTMLGGYNIS PLIELLDDAE VGTVAAEALK 

       130        140        150        160        170        180 
KTLLMFDAFH DVKEKADQGN ANAKAVLQSW ADAEWFTSRP EVPQSLTITV FKVPGETNTD 

       190        200        210        220        230        240 
DLSPAPDATT RPDIPMHALA MLKNKREGAA FQPEEDGKRG PVKFIESLKE KGHLVAYVGD 

       250        260        270        280        290        300 
VVGTGSSRKS ATNSVLWFTG EDIPFIPNKR FGGVCLGNKI APIFYNTMED AGALPIELDV 

       310        320        330        340        350        360 
SKMEMGDVVE LRPYEGKALK DGAVIAEFKV KSDVLFDEVR AGGRIPLIVG RGLTAKAREA 

       370        380        390        400        410        420 
LGLAPSTLFR LPQNPADTGR GFTLAQKMVG RACGLPEGKG IRPGTYCEPK MTSVGSQDTT 

       430        440        450        460        470        480 
GPMTRDELKD LACLGFSADL VMQSFCHTAA YPKPVDVKTH HTLPEFISTR GGISLRPGDG 

       490        500        510        520        530        540 
VIHSWLNRML LPDTVGTGGD SHTRFPIGIS FPAGSGLVAF AAATGVMPLD MPESVLVRFK 

       550        560        570        580        590        600 
GKMQPGVTLR DLVNAIPLYA IKQGLLTVAK QGKKNIFSGR VLEIEGLPDL KVEQAFELSD 

       610        620        630        640        650        660 
ASAERSAAGC TVRLNKDPII EYINSNITLL KWMIAQGYQD PRSLQRRIKA MEAWLADPKL 

       670        680        690        700        710        720 
LEPDADAEYA AVIEIDLADV HEPIVACPND PDDVKTLSEV AGAKIDEVFI GSCMTNIGHF 

       730        740        750        760        770        780 
RAASKLLEGK RDIPVKLWVA PPTKMDQKQL TEEGHYGVFG TAGARTEMPG CSLCMGNQAQ 

       790        800        810        820        830        840 
VREGATVMST STRNFPNRLG KNTNVYLGSA ELAAICSRLG RIPTKEEYMA DMGVLNANGD 

       850        860 
KIYKYMNFDQ IEDFKEVADG VTV 

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References

[1]"Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16."
Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R., Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I., Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.
Nat. Biotechnol. 24:1257-1262(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM260480 Genomic DNA. Translation: CAJ95365.1.
RefSeqYP_728730.1. NC_008314.1.

3D structure databases

ProteinModelPortalQ0K3Q9.
SMRQ0K3Q9. Positions 1-861.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING381666.H16_B0568.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ95365; CAJ95365; H16_B0568.
GeneID4456731.
KEGGreh:H16_B0568.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1049.
HOGENOMHOG000205991.
KOK01682.
OMAVGKACGL.
OrthoDBEOG6N944W.
ProtClustDBPRK09238.

Enzyme and pathway databases

BioCycCNEC381666:GJUJ-4275-MONOMER.
UniPathwayUPA00223; UER00718.

Family and domain databases

Gene3D3.20.19.10. 1 hit.
3.30.499.10. 2 hits.
3.40.1060.10. 1 hit.
InterProIPR015931. Acnase/IPM_dHydase_lsu_aba_1/3.
IPR015937. Acoase/IPM_deHydtase.
IPR001030. Acoase/IPM_deHydtase_lsu_aba.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR015932. Aconitase/IPMdHydase_lsu_aba_2.
IPR018136. Aconitase_4Fe-4S_BS.
IPR004406. Aconitase_B_bac.
IPR015930. Aconitase_B_FeS-bd_bac.
IPR015933. Aconitase_B_HEAT-like_bac.
IPR015929. Aconitase_B_N_bac.
[Graphical view]
PANTHERPTHR11670. PTHR11670. 1 hit.
PTHR11670:SF3. PTHR11670:SF3. 1 hit.
PfamPF00330. Aconitase. 2 hits.
PF06434. Aconitase_2_N. 1 hit.
PF11791. Aconitase_B_N. 1 hit.
[Graphical view]
PIRSFPIRSF036687. AcnB. 1 hit.
SUPFAMSSF52016. SSF52016. 1 hit.
SSF53732. SSF53732. 1 hit.
SSF74778. SSF74778. 1 hit.
TIGRFAMsTIGR00117. acnB. 1 hit.
PROSITEPS00450. ACONITASE_1. 1 hit.
PS01244. ACONITASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0K3Q9_CUPNH
AccessionPrimary (citable) accession number: Q0K3Q9
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)