Q0JAA0 (P2C44_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 44
Short name=OsPP2C44
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os04g0609600, LOC_Os04g52000
ORF Names:	OSJNBa0085I10.2

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence CAE03557.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 321	321	Probable protein phosphatase 2C 44		PRO_0000363291
Regions
	Domain	69 – 312	244	PP2C-like
	Compositional bias	9 – 30	22	Ser-rich
Sites
	Metal binding	107	1	Manganese 1 By similarity
	Metal binding	107	1	Manganese 2 By similarity
	Metal binding	108	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	271	1	Manganese 2 By similarity
	Metal binding	310	1	Manganese 2 By similarity
Experimental info
	Sequence conflict	51	1	N → D in AK070129. Ref.4
	Sequence conflict	260	1	N → S in AK070129. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q0JAA0 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 797BA13B5E9CEDAD	FASTA	321	34,773
	10 20 30 40 50 60 MVGRMERQSA SSSASCSPSS SAAGTSSSSS ACGGKKRPDI LNMIRSATCL NSSSTDTGKG 70 80 90 100 110 120 RSKQSSNKVT HGFHLVEGKS GHDMEDYHVA EYKYDKSHEL GLFAIFDGHL GDSVPSYLKA 130 140 150 160 170 180 NLFCNILKEP IFWTNPQEAI KNAYRSTNKY ILENAKQLGP GGSTAVTAIV VDGKDMWVAN 190 200 210 220 230 240 VGDSRAVVCE RGAANQLTVD HEPHTTNERQ RIEKQGGFVT TFPGDVPRVN GQLAVARAFG 250 260 270 280 290 300 DQSLKAHLSS EPDVRHVPIN SSIEFVILAS DGLWKVMKNQ EAVDLVKSIK DPQAAAKRLT 310 320 TEALARKSKD DISCIVIRFR C

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of rice chromosome 4." Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B. Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL606684 Genomic DNA. Translation: CAE03557.1. Sequence problems. AP008210 Genomic DNA. Translation: BAF15737.1. AK070129 mRNA. No translation available.
RefSeq	NP_001053823.1. NM_001060358.1.
UniGene	Os.11204.
3D structure databases
ProteinModelPortal	Q0JAA0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os04g52000.1; LOC_Os04g52000.1; LOC_Os04g52000.
GeneID	4336940.
KEGG	osa:4336940.
Organism-specific databases
Gramene	Q0JAA0.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	VDGKDMW.
ProtClustDB	CLSN2695099.
Gene expression databases
ArrayExpress	Q0JAA0.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C44_ORYSJ

Accession

Primary (citable) accession number: Q0JAA0
Secondary accession number(s): Q7XPM4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	October 3, 2006
Last modified:	April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program