ID   ABAH3_ORYSJ             Reviewed;         500 AA.
AC   Q0J185; Q67TP6;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   24-MAR-2009, entry version 24.
DE   RecName: Full=Abscisic acid 8'-hydroxylase 3;
DE            Short=ABA 8'-hydroxylase 3;
DE            EC=1.14.13.93;
DE   AltName: Full=OsABA8ox3;
DE   AltName: Full=Cytochrome P450 707A7;
GN   Name=CYP707A7; Synonyms=ABA8OX3;
GN   OrderedLocusNames=Os09g0457100, LOC_Os09g28390;
GN   ORFNames=B1342C04.43, OsJ_028469;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17210932; DOI=10.1101/gr.5509507;
RG   The rice annotation project (RAP);
RT   "Curated genome annotation of Oryza sativa ssp. japonica and
RT   comparative genome analysis with Arabidopsis thaliana.";
RL   Genome Res. 17:175-183(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [4]
RP   IDENTIFICATION, AND LACK OF INDUCTION.
RX   PubMed=17205969; DOI=10.1093/pcp/pcm003;
RA   Saika H., Okamoto M., Miyoshi K., Kushiro T., Shinoda S., Jikumaru Y.,
RA   Fujimoto M., Arikawa T., Takahashi H., Ando M., Arimura S., Miyao A.,
RA   Hirochika H., Kamiya Y., Tsutsumi N., Nambara E., Nakazono M.;
RT   "Ethylene promotes submergence-induced expression of OsABA8ox1, a gene
RT   that encodes ABA 8'-hydroxylase in rice.";
RL   Plant Cell Physiol. 48:287-298(2007).
CC   -!- FUNCTION: Involved in the oxidative degradation of abscisic acid
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: (+)-abscisate + NADPH + O(2) = 8'-
CC       hydroxyabscisate + NADP(+) + H(2)O.
CC   -!- COFACTOR: Heme group (By similarity).
CC   -!- PATHWAY: Plant hormone degradation; abscisic acid degradation.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
CC       (Potential).
CC   -!- INDUCTION: Not induced by ethylene treatment or flooding.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD38475.1; Type=Erroneous gene model prediction;
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DR   EMBL; AP006057; BAD38475.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008215; BAF25280.1; -; Genomic_DNA.
DR   EMBL; CM000146; EAZ44986.1; -; Genomic_DNA.
DR   RefSeq; NP_001063366.1; -.
DR   UniGene; Os.81771; -.
DR   GeneID; 4347261; -.
DR   KEGG; osa:4347261; -.
DR   Gramene; Q67TP6; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017973; Cyt_P450_C.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; NADP;
KW   Oxidoreductase; Transmembrane.
FT   CHAIN         1    500       Abscisic acid 8'-hydroxylase 3.
FT                                /FTId=PRO_0000288648.
FT   TRANSMEM      3     23       Potential.
FT   METAL       426    426       Iron (heme axial ligand) (By similarity).
SQ   SEQUENCE   500 AA;  56167 MW;  8F4D0470C0644203 CRC64;
     MAASFVIVIV ISFFISLAFM CYVHYTSRQR RKLHGYGHEK AVRLPPGSMG WPYIGETLQL
     YSQDPNVFFA SKQKRYGEIF KTHILGCPCV MLASPEAARF VLVTQAHLFK PTYPRSKERM
     IGPSALFFHQ GDYHLRLRKL VQGPLGPDAL RALVPDVEAA VRSTLASWDG NVSSTFHAMK
     RLSFDVGIVT IFGGRLDERR KAELRQNYAI VEKGYNSFPN SFPGTLYYKA IQARRRLHGV
     LSDIMRERRA RGEPGSDLLG CLMQSRAGDD GALLTDEQVA DNIIGVLFAA QDTTASVLTW
     IVKYLHDHPK LLEAVRAEQA AIRAANDGGR LPLTWAQTRS MALTHKVILE SLRMASIISF
     TFREAVADVE YKGFLIPKGW KVMPLFRNIH HNPDYFQDPQ KFDPSRFKVS PRPNTFMPFG
     NGVHACPGNE LAKLEMLVLI HHLVTGYRWE IVGSSDEVEY SPFPVPKHGL LAKLWRDDSV
     SVETDGCQNG DNDDNGVAMV
//