Reviewed, UniProtKB/Swiss-Prot Q0J185 (ABAH3_ORYSJ)

Names and origin

Protein names

Recommended name:
    Abscisic acid 8'-hydroxylase 3
      Short name=ABA 8'-hydroxylase 3
    EC=1.14.13.93
Alternative name(s):
    OsABA8ox3
    Cytochrome P450 707A7

Gene names

Name:	CYP707A7
Synonyms:	ABA8OX3
Ordered Locus Names:	Os09g0457100, LOC_Os09g28390
ORF Names:	B1342C04.43, OsJ_028469

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Involved in the oxidative degradation of abscisic acid By similarity.
Catalytic activity	+-abscisate + NADPH + O2 = 8'-hydroxyabscisate + NADP+ + H2O.
Cofactor	Heme group By similarity.
Pathway	Plant hormone degradation; abscisic acid degradation.
Subcellular location	Membrane; Single-pass membrane protein Potential.
Induction	Not induced by ethylene treatment or flooding. Ref.4
Sequence similarities	Belongs to the cytochrome P450 family.
Sequence caution	The sequence BAD38475.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding NADP
Molecular function	Monooxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	(+)-abscisic acid 8'-hydroxylase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Abscisic acid 8'-hydroxylase 3		PRO_0000288648
Regions
	Transmembrane	3 – 23	21	Potential
Sites
	Metal binding	426	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0J185-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 8F4D0470C0644203	FASTA	500	56,167
	10 20 30 40 50 60 MAASFVIVIV ISFFISLAFM CYVHYTSRQR RKLHGYGHEK AVRLPPGSMG WPYIGETLQL 70 80 90 100 110 120 YSQDPNVFFA SKQKRYGEIF KTHILGCPCV MLASPEAARF VLVTQAHLFK PTYPRSKERM 130 140 150 160 170 180 IGPSALFFHQ GDYHLRLRKL VQGPLGPDAL RALVPDVEAA VRSTLASWDG NVSSTFHAMK 190 200 210 220 230 240 RLSFDVGIVT IFGGRLDERR KAELRQNYAI VEKGYNSFPN SFPGTLYYKA IQARRRLHGV 250 260 270 280 290 300 LSDIMRERRA RGEPGSDLLG CLMQSRAGDD GALLTDEQVA DNIIGVLFAA QDTTASVLTW 310 320 330 340 350 360 IVKYLHDHPK LLEAVRAEQA AIRAANDGGR LPLTWAQTRS MALTHKVILE SLRMASIISF 370 380 390 400 410 420 TFREAVADVE YKGFLIPKGW KVMPLFRNIH HNPDYFQDPQ KFDPSRFKVS PRPNTFMPFG 430 440 450 460 470 480 NGVHACPGNE LAKLEMLVLI HHLVTGYRWE IVGSSDEVEY SPFPVPKHGL LAKLWRDDSV 490 500 SVETDGCQNG DNDDNGVAMV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Ethylene promotes submergence-induced expression of OsABA8ox1, a gene that encodes ABA 8'-hydroxylase in rice." Saika H., Okamoto M., Miyoshi K., Kushiro T., Shinoda S., Jikumaru Y., Fujimoto M., Arikawa T., Takahashi H., Ando M., Arimura S., Miyao A., Hirochika H., Kamiya Y., Tsutsumi N., Nambara E., Nakazono M. Plant Cell Physiol. 48:287-298(2007) [PubMed: 17205969] [Abstract] Cited for: IDENTIFICATION, LACK OF INDUCTION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006057 Genomic DNA. Translation: BAD38475.1. Sequence problems. AP008215 Genomic DNA. Translation: BAF25280.1. CM000146 Genomic DNA. Translation: EAZ44986.1.
RefSeq	NP_001063366.1.
UniGene	Os.81771
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4347261.
GenomeReviews	Gene locus CYP707A7 in contig AP008215_GR.
KEGG	osa:4347261.
Organism-specific databases
Gramene	Q67TP6.
Family and domain databases
InterPro	IPR001128. Cyt_P450. IPR017973. Cyt_P450_C. IPR017972. Cyt_P450_CS. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Gene3D	G3DSA:1.10.630.10. Cyt_P450. 1 hit.
PANTHER	PTHR19383. Cyt_P450. 1 hit.
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABAH3_ORYSJ

Accession

Primary (citable) accession number: Q0J185
Secondary accession number(s): Q67TP6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	October 3, 2006
Last modified:	October 13, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)