Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Pyruvate dehydrogenase E1 component subunit beta-2, mitochondrial

Gene

Os09g0509200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).By similarity

Catalytic activityi

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei99Thiamine pyrophosphateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processGlycolysis
LigandPyruvate, Thiamine pyrophosphate

Enzyme and pathway databases

ReactomeiR-OSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex
R-OSA-5362517 Signaling by Retinoic Acid
R-OSA-70268 Pyruvate metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate dehydrogenase E1 component subunit beta-2, mitochondrial (EC:1.2.4.1)
Short name:
PDHE1-B
Gene namesi
Ordered Locus Names:Os09g0509200, LOC_Os09g33500
ORF Names:OsJ_29962
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 36MitochondrionSequence analysisAdd BLAST36
ChainiPRO_000042137437 – 376Pyruvate dehydrogenase E1 component subunit beta-2, mitochondrialAdd BLAST340

Proteomic databases

PaxDbiQ0J0H4
PRIDEiQ0J0H4

Expressioni

Gene expression databases

ExpressionAtlasiQ0J0H4 baseline and differential
GenevisibleiQ0J0H4 OS

Interactioni

Subunit structurei

Tetramer of 2 alpha and 2 beta subunits.By similarity

Protein-protein interaction databases

STRINGi39947.LOC_Os09g33500.1

Structurei

3D structure databases

ProteinModelPortaliQ0J0H4
SMRiQ0J0H4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0524 Eukaryota
COG0022 LUCA
InParanoidiQ0J0H4
KOiK00162
OMAiYWLKGEV
OrthoDBiEOG09360DY5

Family and domain databases

Gene3Di3.40.50.920, 1 hit
InterProiView protein in InterPro
IPR027110 PDHB
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR033248 Transketolase_C
PANTHERiPTHR11624:SF94 PTHR11624:SF94, 1 hit
PfamiView protein in Pfam
PF02779 Transket_pyr, 1 hit
PF02780 Transketolase_C, 1 hit
SMARTiView protein in SMART
SM00861 Transket_pyr, 1 hit
SUPFAMiSSF52518 SSF52518, 1 hit
SSF52922 SSF52922, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0J0H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGAARRQLG SGPMLGQVLR RLRPATAAAA DAARAYSAAA KEMTVREALN
60 70 80 90 100
SALDEEMSAD PSVFLMGEEV GEYQGAYKIS KGLLDKYGPE RVLDTPITEA
110 120 130 140 150
GFTGIAVGAA YQGLRPVVEF MTFNFSMQAI DHIINSAAKS NYMSAGQISV
160 170 180 190 200
PIVFRGPNGA AAGVGAQHSQ CYAAWYAHVP GLKVLVPYSA EDARGLLKAA
210 220 230 240 250
IRDPDPVVFL ENELLYGESF PISAEVLDSS FALPIGKAKI EREGKDVTIT
260 270 280 290 300
AYSKMVGYAL QAADILSKEG ISAEVINLRS IRPLDRATIN ASVRKTNRLV
310 320 330 340 350
TIEESFPQHG IGAEICMSVV EESFEYLDAP VERIAGADVP MPYAANLERM
360 370
AVPQVDDIVR AAKRACYRAV PMAATA
Length:376
Mass (Da):40,251
Last modified:October 3, 2006 - v1
Checksum:i53CF7C6FB2189741
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008215 Genomic DNA Translation: BAF25541.1
AP014965 Genomic DNA Translation: BAT08892.1
CM000146 Genomic DNA Translation: EEE70023.1
AK069525 mRNA Translation: BAG91472.1
RefSeqiXP_015612322.1, XM_015756836.1
UniGeneiOs.9587

Genome annotation databases

EnsemblPlantsiOs09t0509200-01; Os09t0509200-01; Os09g0509200
GeneIDi4347531
GrameneiOs09t0509200-01; Os09t0509200-01; Os09g0509200
KEGGiosa:4347531

Similar proteinsi

Entry informationi

Entry nameiODPB2_ORYSJ
AccessioniPrimary (citable) accession number: Q0J0H4
Secondary accession number(s): A0A0P0XPJ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2013
Last sequence update: October 3, 2006
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health