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Q0J006

- PSA7B_ORYSJ

UniProt

Q0J006 - PSA7B_ORYSJ

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Protein
Proteasome subunit alpha type-7-B
Gene
PAD1, Os09g0538200, LOC_Os09g36710, OsJ_028982, P0229B10.22, P0569E11.44
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.

GO - Molecular functioni

  1. threonine-type endopeptidase activity Source: UniProtKB-KW

GO - Biological processi

  1. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Threonine protease

Enzyme and pathway databases

ReactomeiREACT_205610. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_205939. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_207219. APC/C:Cdc20 mediated degradation of Securin.
REACT_212204. Separation of Sister Chromatids.
REACT_214064. ER-Phagosome pathway.
REACT_219834. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_223172. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit alpha type-7-B (EC:3.4.25.1)
Alternative name(s):
20S proteasome alpha subunit D-2
20S proteasome subunit alpha-4-B
Gene namesi
Name:PAD1
Ordered Locus Names:Os09g0538200, LOC_Os09g36710
ORF Names:OsJ_028982, P0229B10.22, P0569E11.44
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 9

Organism-specific databases

GrameneiQ0J006.

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. chloroplast Source: EnsemblPlants/Gramene
  2. cytosolic ribosome Source: EnsemblPlants/Gramene
  3. nucleus Source: UniProtKB-SubCell
  4. phragmoplast Source: EnsemblPlants/Gramene
  5. proteasome core complex, alpha-subunit complex Source: InterPro
  6. spindle Source: EnsemblPlants/Gramene
  7. vacuolar membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 249249Proteasome subunit alpha type-7-B
PRO_0000124163Add
BLAST

Proteomic databases

PaxDbiQ0J006.
PRIDEiQ0J006.

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

Structurei

3D structure databases

ProteinModelPortaliQ0J006.
SMRiQ0J006. Positions 4-231.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1A family.

Phylogenomic databases

eggNOGiCOG0638.
KOiK02731.
OMAiITRHIAG.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiIPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
PfamiPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTiSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiPS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0J006-1 [UniParc]FASTAAdd to Basket

« Hide

MARYDRAITV FSPDGHLFQV EYALEAVRKG NAAVGVRGSD TVVLGVEKKS    50
TPKLQDSRSV RKIASLDTHI ALACAGLKAD ARVLINRARV ECQSHRLTVE 100
DAVTVEYITR YIAGLQQKYT QSGGVRPFGL STLIVGFDPY TDKPALYQTD 150
PSGTFSAWKA NATGRNSNSM REFLEKNYKE TSGKETIKLA IRALLEVVES 200
GGKNIEIAVM TQKDGLRQLE EAEIDEYVAE IEAEKAAAEA AKKGAPKET 249
Length:249
Mass (Da):27,214
Last modified:October 3, 2006 - v1
Checksum:iD20D0B27143D976E
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti85 – 851Missing in BAA99540. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032061 mRNA. Translation: BAA99540.1.
AP006067 Genomic DNA. Translation: BAD34241.1.
AP006174 Genomic DNA. Translation: BAD34378.1.
AP008215 Genomic DNA. Translation: BAF25709.1.
CM000146 Genomic DNA. Translation: EAZ45499.1.
RefSeqiNP_001063795.1. NM_001070330.1.
UniGeneiOs.3737.

Genome annotation databases

EnsemblPlantsiOS09T0538200-01; OS09T0538200-01; OS09G0538200.
GeneIDi4347710.
KEGGiosa:4347710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032061 mRNA. Translation: BAA99540.1 .
AP006067 Genomic DNA. Translation: BAD34241.1 .
AP006174 Genomic DNA. Translation: BAD34378.1 .
AP008215 Genomic DNA. Translation: BAF25709.1 .
CM000146 Genomic DNA. Translation: EAZ45499.1 .
RefSeqi NP_001063795.1. NM_001070330.1.
UniGenei Os.3737.

3D structure databases

ProteinModelPortali Q0J006.
SMRi Q0J006. Positions 4-231.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q0J006.
PRIDEi Q0J006.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS09T0538200-01 ; OS09T0538200-01 ; OS09G0538200 .
GeneIDi 4347710.
KEGGi osa:4347710.

Organism-specific databases

Gramenei Q0J006.

Phylogenomic databases

eggNOGi COG0638.
KOi K02731.
OMAi ITRHIAG.

Enzyme and pathway databases

Reactomei REACT_205610. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_205939. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_207219. APC/C:Cdc20 mediated degradation of Securin.
REACT_212204. Separation of Sister Chromatids.
REACT_214064. ER-Phagosome pathway.
REACT_219834. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_223172. Antigen processing: Ubiquitination & Proteasome degradation.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
InterProi IPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view ]
Pfami PF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view ]
SMARTi SM00948. Proteasome_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
PROSITEi PS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structural features of the 20S proteasome subunits of rice (Oryza sativa)."
    Sassa H., Oguchi S., Inoue T., Hirano H.
    Gene 250:61-66(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiPSA7B_ORYSJ
AccessioniPrimary (citable) accession number: Q0J006
Secondary accession number(s): O04861, Q69JF0, Q9LRI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 3, 2006
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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