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Q0J006 (PSA7B_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteasome subunit alpha type-7-B

EC=3.4.25.1
Alternative name(s):
20S proteasome alpha subunit D-2
20S proteasome subunit alpha-4-B
Gene names
Name:PAD1
Ordered Locus Names:Os09g0538200, LOC_Os09g36710
ORF Names:OsJ_028982, P0229B10.22, P0569E11.44
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activity

Cleavage of peptide bonds with very broad specificity.

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the peptidase T1A family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249Proteasome subunit alpha type-7-B
PRO_0000124163

Experimental info

Sequence conflict851Missing in BAA99540. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q0J006 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: D20D0B27143D976E

FASTA24927,214
        10         20         30         40         50         60 
MARYDRAITV FSPDGHLFQV EYALEAVRKG NAAVGVRGSD TVVLGVEKKS TPKLQDSRSV 

        70         80         90        100        110        120 
RKIASLDTHI ALACAGLKAD ARVLINRARV ECQSHRLTVE DAVTVEYITR YIAGLQQKYT 

       130        140        150        160        170        180 
QSGGVRPFGL STLIVGFDPY TDKPALYQTD PSGTFSAWKA NATGRNSNSM REFLEKNYKE 

       190        200        210        220        230        240 
TSGKETIKLA IRALLEVVES GGKNIEIAVM TQKDGLRQLE EAEIDEYVAE IEAEKAAAEA 


AKKGAPKET 

« Hide

References

« Hide 'large scale' references
[1]"Primary structural features of the 20S proteasome subunits of rice (Oryza sativa)."
Sassa H., Oguchi S., Inoue T., Hirano H.
Gene 250:61-66(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB032061 mRNA. Translation: BAA99540.1.
AP006067 Genomic DNA. Translation: BAD34241.1.
AP006174 Genomic DNA. Translation: BAD34378.1.
AP008215 Genomic DNA. Translation: BAF25709.1.
CM000146 Genomic DNA. Translation: EAZ45499.1.
RefSeqNP_001063795.1. NM_001070330.1.
UniGeneOs.3737.

3D structure databases

ProteinModelPortalQ0J006.
SMRQ0J006. Positions 4-231.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ0J006.
PRIDEQ0J006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS09T0538200-01; OS09T0538200-01; OS09G0538200.
GeneID4347710.
KEGGosa:4347710.

Organism-specific databases

GrameneQ0J006.

Phylogenomic databases

eggNOGCOG0638.
KOK02731.
OMAITRHIAG.

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSA7B_ORYSJ
AccessionPrimary (citable) accession number: Q0J006
Secondary accession number(s): O04861, Q69JF0, Q9LRI3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 3, 2006
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

Peptidase families

Classification of peptidase families and list of entries