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Q0IQU1

- LAC22_ORYSJ

UniProt

Q0IQU1 - LAC22_ORYSJ

Protein

Laccase-22

Gene

LAC22

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 2 (26 Jun 2007)
      Previous versions | rss
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    Functioni

    Lignin degradation and detoxification of lignin-derived products.By similarity

    Catalytic activityi

    4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

    Cofactori

    Binds 4 copper ions per monomer.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi86 – 861Copper 1By similarity
    Metal bindingi88 – 881Copper 2By similarity
    Metal bindingi131 – 1311Copper 2By similarity
    Metal bindingi133 – 1331Copper 3By similarity
    Metal bindingi465 – 4651Copper 4By similarity
    Metal bindingi468 – 4681Copper 1By similarity
    Metal bindingi470 – 4701Copper 3By similarity
    Metal bindingi527 – 5271Copper 3By similarity
    Metal bindingi528 – 5281Copper 4By similarity
    Metal bindingi529 – 5291Copper 2By similarity
    Metal bindingi533 – 5331Copper 4By similarity

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lignin catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Lignin degradation

    Keywords - Ligandi

    Copper, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Laccase-22 (EC:1.10.3.2)
    Alternative name(s):
    Benzenediol:oxygen oxidoreductase 22
    Diphenol oxidase 22
    Urishiol oxidase 22
    Gene namesi
    Name:LAC22
    Ordered Locus Names:Os11g0708100, LOC_Os11g48060
    ORF Names:OsJ_033548
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 11

    Organism-specific databases

    GrameneiQ0IQU1.

    Subcellular locationi

    GO - Cellular componenti

    1. apoplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Apoplast, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 564539Laccase-22PRO_0000291909Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi41 – 411N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi82 – 821N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi118 – 1181N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi191 – 1911N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi302 – 3021N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi331 – 3311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi379 – 3791N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi389 – 3891N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi424 – 4241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi437 – 4371N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi447 – 4471N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi39947.LOC_Os11g48060.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0IQU1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini36 – 152117Plastocyanin-like 1Add
    BLAST
    Domaini162 – 314153Plastocyanin-like 2Add
    BLAST
    Domaini414 – 548135Plastocyanin-like 3Add
    BLAST

    Sequence similaritiesi

    Belongs to the multicopper oxidase family.Curated
    Contains 3 plastocyanin-like domains.Curated

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiCOG2132.
    HOGENOMiHOG000241916.

    Family and domain databases

    Gene3Di2.60.40.420. 3 hits.
    InterProiIPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    IPR017761. Laccase.
    [Graphical view]
    PfamiPF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49503. SSF49503. 3 hits.
    TIGRFAMsiTIGR03389. laccase. 1 hit.
    PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q0IQU1-1 [UniParc]FASTAAdd to Basket

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    MAVLPESRRL SLLLMAACFL LQALSAHAIT RHYKFNVVMR NMTRLCSTKP    50
    ILTVNGKFPG PTLYAREGDN VLVKVVNHVA HNVTIHWHGV RQIRTGWYDG 100
    PAYITQCPIQ PGSSFLYNFT ITGQRGTLLW HAHINWLRAT VHGAIVILPK 150
    LGVPYPFPAP HKEAVIVLGE WWKEDTETVI NQAMQLGVGP NISDSHTING 200
    HPGPLSECAS SQDGFKLSVE NGKTYMLRII NAALNDDLFF KVAGHELTVV 250
    EVDAVYTKPF KTDTLLITPG QTTNVLVRAN QGAGRYLLSV SPFMDAPVQV 300
    DNKTGTATLH YANTVSSSMA SLTLVKPPPQ NATHIVSKFT DSLHSLNSKE 350
    YPANVPQTVD HSLLLTVGVG VNPCPSCING TRVVGTINNV TFIMPSTPIL 400
    QAHYYNIPGV FTEDFPATPL HKFNYTGSGP KNLQTMNGTR VYRLPYNASV 450
    QVVLQDTGII SPESHPIHLH GFNFFVVGKG VGNYNPRTSP STFNLIDPIE 500
    RNTIGVPTGG WTAIRFRSDN PGVWFMHCHF EVHTSWGLKM AFVVDNGKRP 550
    SETLIPPPKD LPQC 564
    Length:564
    Mass (Da):62,042
    Last modified:June 26, 2007 - v2
    Checksum:iC88700E8EDA0C0D2
    GO

    Sequence cautioni

    The sequence BAF28924.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC133008 Genomic DNA. Translation: AAX95423.1.
    DP000010 Genomic DNA. Translation: ABA95532.1.
    AP008217 Genomic DNA. Translation: BAF28924.1. Sequence problems.
    CM000148 Genomic DNA. Translation: EAZ19339.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC133008 Genomic DNA. Translation: AAX95423.1 .
    DP000010 Genomic DNA. Translation: ABA95532.1 .
    AP008217 Genomic DNA. Translation: BAF28924.1 . Sequence problems.
    CM000148 Genomic DNA. Translation: EAZ19339.1 .

    3D structure databases

    ProteinModelPortali Q0IQU1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 39947.LOC_Os11g48060.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei Q0IQU1.

    Phylogenomic databases

    eggNOGi COG2132.
    HOGENOMi HOG000241916.

    Family and domain databases

    Gene3Di 2.60.40.420. 3 hits.
    InterProi IPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    IPR017761. Laccase.
    [Graphical view ]
    Pfami PF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49503. SSF49503. 3 hits.
    TIGRFAMsi TIGR03389. laccase. 1 hit.
    PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
      The rice chromosomes 11 and 12 sequencing consortia
      BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiLAC22_ORYSJ
    AccessioniPrimary (citable) accession number: Q0IQU1
    Secondary accession number(s): Q53NW2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 26, 2007
    Last sequence update: June 26, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3