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Q0IP28

- LAC25_ORYSJ

UniProt

Q0IP28 - LAC25_ORYSJ

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Protein
Laccase-25
Gene
LAC25, Os12g0259800, LOC_Os12g15920
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi81 – 811Copper 1 By similarity
Metal bindingi83 – 831Copper 2 By similarity
Metal bindingi126 – 1261Copper 2 By similarity
Metal bindingi128 – 1281Copper 3 By similarity
Metal bindingi477 – 4771Copper 4 By similarity
Metal bindingi480 – 4801Copper 1 By similarity
Metal bindingi482 – 4821Copper 3 By similarity
Metal bindingi539 – 5391Copper 3 By similarity
Metal bindingi540 – 5401Copper 4 By similarity
Metal bindingi541 – 5411Copper 2 By similarity
Metal bindingi545 – 5451Copper 4 By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-25 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 25
Diphenol oxidase 25
Urishiol oxidase 25
Gene namesi
Name:LAC25
Ordered Locus Names:Os12g0259800, LOC_Os12g15920
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 12

Organism-specific databases

GrameneiQ0IP28.

Subcellular locationi

Secretedextracellular spaceapoplast Reviewed prediction

GO - Cellular componenti

  1. apoplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed prediction
Add
BLAST
Chaini23 – 577555Laccase-25
PRO_0000291912Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi33 – 331N-linked (GlcNAc...) Reviewed prediction
Glycosylationi109 – 1091N-linked (GlcNAc...) Reviewed prediction
Glycosylationi169 – 1691N-linked (GlcNAc...) Reviewed prediction
Glycosylationi203 – 2031N-linked (GlcNAc...) Reviewed prediction
Glycosylationi208 – 2081N-linked (GlcNAc...) Reviewed prediction
Glycosylationi218 – 2181N-linked (GlcNAc...) Reviewed prediction
Glycosylationi332 – 3321N-linked (GlcNAc...) Reviewed prediction
Glycosylationi383 – 3831N-linked (GlcNAc...) Reviewed prediction
Glycosylationi396 – 3961N-linked (GlcNAc...) Reviewed prediction
Glycosylationi404 – 4041N-linked (GlcNAc...) Reviewed prediction
Glycosylationi441 – 4411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi459 – 4591N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15920.1.

Structurei

3D structure databases

ProteinModelPortaliQ0IP28.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 147118Plastocyanin-like 1
Add
BLAST
Domaini158 – 313156Plastocyanin-like 2
Add
BLAST
Domaini423 – 560138Plastocyanin-like 3
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0IP28-1 [UniParc]FASTAAdd to Basket

« Hide

MTLHWSLLLF IAIALVSSVA QAAVVEHTFN VGNFSISQLC QPPLIITAVN    50
GQLPGPTIYA REGDTVVVHL VNTSPYSMTL HWHGVLQRGT PWADGPAMVT 100
QCPVQPGGNY TYRFNVDGQE GTLWWHAHVS FHRATVYGAL VIRPRGGAKA 150
YPFPKPDKEH VVILGEWWNA TVYDMERMAF LTGIPAPHAD AYTINGKPGD 200
FYNCSAPNQT AKFEVRQNGT YLLRIINAGM NTPLFFKVAK HRLTVVGADA 250
CYTKPYKTDV VVVSPGQTVD ALMVASAAVG RYYMAASPYD SAIPQGPPFS 300
DTTATAILQY AGARRKTVRW RPPVLPRRPP VNDTATAHRF FSGMTALLRH 350
GKPSAVPLAV DTHMYVTVGL GVSLCQPEQL LCNRSAPPVF SSSMNNASFV 400
VPKNTSLLEA HFRREPAGVY TRDFPDTPPV VFDYTGDESD NATMQFTTKS 450
TKVKTLRYNE TVEMVLQNTR LIAKESHPMH IHGFNFFILA QGFGNYDKRR 500
AERRFNLVDP QERNTIAVPT GGWAVIRFVA DNPGMWYMHC HFDAHISLGL 550
AMVLEVLDGP TPETSVPPPP ADLPRCS 577
Length:577
Mass (Da):63,680
Last modified:October 3, 2006 - v1
Checksum:iCA6FE93780DD7AA1
GO

Sequence cautioni

The sequence ABA97328.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000011 Genomic DNA. Translation: ABA97328.1. Sequence problems.
AP008218 Genomic DNA. Translation: BAF29537.1.
RefSeqiNP_001066518.1. NM_001073050.1.
UniGeneiOs.78608.

Genome annotation databases

GeneIDi4351917.
KEGGiosa:4351917.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000011 Genomic DNA. Translation: ABA97328.1 . Sequence problems.
AP008218 Genomic DNA. Translation: BAF29537.1 .
RefSeqi NP_001066518.1. NM_001073050.1.
UniGenei Os.78608.

3D structure databases

ProteinModelPortali Q0IP28.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os12g15920.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4351917.
KEGGi osa:4351917.

Organism-specific databases

Gramenei Q0IP28.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 4 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC25_ORYSJ
AccessioniPrimary (citable) accession number: Q0IP28
Secondary accession number(s): Q2QUK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: October 3, 2006
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi