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Protein

Metallothionein-like protein 4A

Gene

MT4A

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-like protein 4A
Alternative name(s):
Class I metallothionein-like protein 4A
OsMT-I-4a
OsMT1b
Gene namesi
Name:MT4A
Ordered Locus Names:Os12g0570700, LOC_Os12g38270
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 12

Organism-specific databases

GrameneiQ0IMG5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7878Metallothionein-like protein 4APRO_0000263059Add
BLAST

Expressioni

Tissue specificityi

Expressed in roots.1 Publication

Gene expression databases

ExpressionAtlasiQ0IMG5. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g38270.1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000220916.
InParanoidiQ0IMG5.

Family and domain databases

InterProiIPR000347. Metalthion_15p.
[Graphical view]
PfamiPF01439. Metallothio_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0IMG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCCGGSCNC GSSCKCGSGC GNMYPDLAEK TTNTSATMVL GVAPAKEQFE
60 70
GVGKAAESGE AAHGCSCGSS CKCNPCNC
Length:78
Mass (Da):7,644
Last modified:October 3, 2006 - v1
Checksum:i4973599B9EBD717F
GO

Sequence cautioni

The sequence ABA99658.2 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA99658.2. Sequence problems.
AP008218 Genomic DNA. Translation: BAF30100.1.
AK103445 mRNA. No translation available.
RefSeqiNP_001067081.1. NM_001073613.1.
UniGeneiOs.9279.

Genome annotation databases

EnsemblPlantsiOS12T0570700-01; OS12T0570700-01; OS12G0570700.
GeneIDi4352580.
KEGGiosa:4352580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA99658.2. Sequence problems.
AP008218 Genomic DNA. Translation: BAF30100.1.
AK103445 mRNA. No translation available.
RefSeqiNP_001067081.1. NM_001073613.1.
UniGeneiOs.9279.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os12g38270.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS12T0570700-01; OS12T0570700-01; OS12G0570700.
GeneIDi4352580.
KEGGiosa:4352580.

Organism-specific databases

GrameneiQ0IMG5.

Phylogenomic databases

HOGENOMiHOG000220916.
InParanoidiQ0IMG5.

Gene expression databases

ExpressionAtlasiQ0IMG5. baseline.

Family and domain databases

InterProiIPR000347. Metalthion_15p.
[Graphical view]
PfamiPF01439. Metallothio_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  5. "Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)."
    Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.
    J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, TISSUE SPECIFICITY.

Entry informationi

Entry nameiMT4A_ORYSJ
AccessioniPrimary (citable) accession number: Q0IMG5
Secondary accession number(s): Q2QNC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 3, 2006
Last modified: June 24, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Metallothioneins
    Classification of metallothioneins and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.