Q0IJ51 (Q0IJ51_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
P2X purinoceptor RuleBase RU000681

Gene names

Name:

P2RX7 EMBL AAI21158.1

Organism

Homo sapiens (Human) EMBL AAI21158.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	554 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Homo- or heteropolymers By similarity. RuleBase RU000681
Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU000681.
Sequence similarities	Belongs to the P2X receptor family. RuleBase RU000681

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000681
Molecular function	Ionic channel RuleBase RU000681 Receptor RuleBase RU000681
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ion channel activity Inferred from electronic annotation. Source: UniProtKB-KW receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	554	1	EMBL AAI21158.1

Sequences

	Sequence		Length	Mass (Da)
	Q0IJ51 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: AF1BF14A51F57B7F	FASTA	554	63,680
	10 20 30 40 50 60 MPACCSCSDV FQYETNKVTR IQSMNYGTIK WFFHVIIFSY VCFALVSDKL YQRKEPVISS 70 80 90 100 110 120 VHTKVKGIAE VKEEIVENGV KKLVHSVFDT ADYTFPLQGN SFFVMTNFLK TEGQEQRLCP 130 140 150 160 170 180 EYPTRRTLCS SDRGCKKGWM DPQSKGIQTG RCVVHEGNQK TCEVSAWCPI EAVEEAPRPA 190 200 210 220 230 240 LLNSAENFTV LIKNNIDFPG HNYTTRNILP GLNITCTFHK TQNPQCPIFR LGDIFRETGD 250 260 270 280 290 300 NFSDVAIQGG IMGIEIYWDC NLDRWFHHCH PKYSFRRLDD KTTNVSLYPG YNFRYAKYYK 310 320 330 340 350 360 ENNVEKRTLI KVFGIRFDIL VFGTGGKFDI IQLVVYIGST LSYFGLAAVF IDFLIDTYSS 370 380 390 400 410 420 NCCRSHIYPW CKCCQPCVVN EYYYRKKCES IVEPKPTLKY VSFVDESHIR MVNQQLLGRS 430 440 450 460 470 480 LQDVKGQEVP RPAMDFTDLS RLPLALHDTP PIPGQPEEIQ LLRKEATPRS RDSPVWCQCG 490 500 510 520 530 540 SCLPSQLPES HRCLEELCCR KKPGACITTS ELFRKLVLSR HVLQFLLLYQ EPLLALDVDS 550 TNSRLRHCAY RCYA

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI21158.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC121157 mRNA. Translation: AAI21158.1.
IPI	IPI00293328.
UniGene	Hs.729169.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0IJ51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG053086.
Gene expression databases
ArrayExpress	Q0IJ51.
Family and domain databases
InterPro	IPR003050. P2X7_purnocptor. IPR001429. P2X_purnocptor. [Graphical view]
PANTHER	PTHR10125. ATP_P2X_rcpt. 1 hit. PTHR10125:SF13. PTHR10125:SF13. 1 hit.
Pfam	PF00864. P2X_receptor. 1 hit. [Graphical view]
PRINTS	PR01314. P2X7RECEPTOR. PR01307. P2XRECEPTOR.
TIGRFAMs	TIGR00863. P2X. 1 hit.
PROSITE	PS01212. P2X_RECEPTOR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0IJ51_HUMAN

Accession

Primary (citable) accession number: Q0IJ51

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.