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Q0IIW3 (SODC_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Cu-Zn]

EC=1.15.1.1
Gene names
Name:sod1
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length151 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. UniProtKB P15107

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2. UniProtKB P15107

Cofactor

Binds 1 copper ion per subunit By similarity. UniProtKB P15107

Binds 1 zinc ion per subunit By similarity. UniProtKB P15107

Subunit structure

Homodimer By similarity. UniProtKB P00441

Subcellular location

Cytoplasm By similarity. Nucleus By similarity UniProtKB P15107.

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity UniProtKB P15107
Chain2 – 151150Superoxide dismutase [Cu-Zn] UniProtKB P15107
PRO_0000392433

Sites

Metal binding451Copper; catalytic By similarity UniProtKB P15107
Metal binding471Copper; catalytic By similarity UniProtKB P15107
Metal binding621Copper; catalytic By similarity UniProtKB P15107
Metal binding621Zinc; structural By similarity UniProtKB P15107
Metal binding701Zinc; structural By similarity UniProtKB P15107
Metal binding791Zinc; structural By similarity UniProtKB P15107
Metal binding821Zinc; structural By similarity UniProtKB P15107
Metal binding1181Copper; catalytic By similarity UniProtKB P15107

Amino acid modifications

Lipidation61S-palmitoyl cysteine By similarity
Disulfide bond56 ↔ 144 By similarity UniProtKB P15107

Sequences

Sequence LengthMass (Da)Tools
Q0IIW3 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 6E4E5F8260D4CD4B

FASTA15115,698
        10         20         30         40         50         60 
MVRAVCVLAG SGDVKGVVHF QQQDEGPVTV EGKIYGLTDG KHGFHIHEFG DNTNGCISAG 

        70         80         90        100        110        120 
PHFNPESKTH GAPEDAVRHV GDLGNVTAKD GVAEFKLTDS LISLKGNHSI IGRCAVVHEK 

       130        140        150 
EDDLGKGGND ESLKTGNAGG RLACGVIGLC Q 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: N6.
Tissue: Oviduct.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC121540 mRNA. Translation: AAI21541.1.
RefSeqNP_001016252.1. NM_001016252.2.
UniGeneStr.1999.

3D structure databases

ProteinModelPortalQ0IIW3.
SMRQ0IIW3. Positions 2-148.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000015994.

Proteomic databases

PaxDbQ0IIW3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID549006.
KEGGxtr:549006.

Organism-specific databases

CTD6647.
XenbaseXB-GENE-1006488. sod1.

Phylogenomic databases

eggNOGCOG2032.
HOGENOMHOG000263447.
HOVERGENHBG000062.
KOK04565.

Family and domain databases

Gene3D2.60.40.200. 1 hit.
InterProIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSPR00068. CUZNDISMTASE.
SUPFAMSSF49329. SSF49329. 1 hit.
PROSITEPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODC_XENTR
AccessionPrimary (citable) accession number: Q0IIW3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: October 3, 2006
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families