Unreviewed, UniProtKB/TrEMBL Q0IIN7 (Q0IIN7_HUMAN)

Names and origin

Protein names

Submitted name:
    Nuclear receptor coactivator 3 EMBL AAI22548.1

Gene names

Name:

NCOA3 EMBL AAI22548.1

Organism

Homo sapiens (Human) EMBL AAI22548.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1419 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367V1 Spearmint SPM000014

Ontologies

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM000014
Cellular component	Nucleus Spearmint SPM000014
Molecular function	Receptor
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	nuclear hormone receptor binding Inferred from electronic annotation. Source: InterPro receptor activity Inferred from electronic annotation. Source: UniProtKB-KW transcription coactivator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0IIN7-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: D519343291E37B7B	FASTA	1,419	154,764
	10 20 30 40 50 60 MSGLGENLDP LASDSRKRKL PCDTPGQGLT CSGEKRRREQ ESKYIEELAE LISANLSDID 70 80 90 100 110 120 NFNVKPDKCA ILKETVRQIR QIKEQGKTIS NDDDVQKADV SSTGQGVIDK DSLGPLLLQA 130 140 150 160 170 180 LDGFLFVVNR DGNIVFVSEN VTQYLQYKQE DLVNTSVYNI LHEEDRKDFL KNLPKSTVNG 190 200 210 220 230 240 VSWTNETQRQ KSHTFNCRML MKTPHDILED INASPEMRQR YETMQCFALS QPRAMMEEGE 250 260 270 280 290 300 DLQSCMICVA RRITTGERTF PSNPESFITR HDLSGKVVNI DTNSLRSSMR PGFEDIIRRC 310 320 330 340 350 360 IQRFFSLNDG QSWSQKRHYQ EAYLNGHAET PVYRFSLADG TIVTAQTKSK LFRNPVTNDR 370 380 390 400 410 420 HGFVSTHFLQ REQNGYRPNP NPVGQGIRPP MAGCNSSVGG MSMSPNQGLQ MPSSRAYGLA 430 440 450 460 470 480 DPSTTGQMSG ARYGGSSNIA SLTPGPGMQS PSSYQNNNYG LNMSSPPHGS PGLAPNQQNI 490 500 510 520 530 540 MISPRNRGSP KIASHQFSPV AGVHSPMASS GNTGNHSFSS SSLSALQAIS EGVGTSLLST 550 560 570 580 590 600 LSSPGPKLDN SPNMNITQPS KVSNQDSKSP LGFYCDQNPV ESSMCQSNSR DHLSDKESKE 610 620 630 640 650 660 SSVEGAENQR GPLESKGHKK LLQLLTCSSD DRGHSSLTNS PLDSSCKESS VSVTSPSGVS 670 680 690 700 710 720 SSTSGGVSST SNMHGSLLQE KHRILHKLLQ NGNSPAEVAK ITAEATGKDT SSITSCGDGN 730 740 750 760 770 780 VVKQEQLSPK KKENNALLRY LLDRDDPSDA LSKELQPQVE GVDNKMSQCT SSTIPSSSQE 790 800 810 820 830 840 KDPKIKTETS EEGSGDLDNL DAILGDLTSS DFYNNSISSN GSHLGTKQQV FQGTNSLGLK 850 860 870 880 890 900 SSQSVQSIRP PYNRAVSLDS PVSVGSSPPV KNISAFPMLP KQPMLGGNPR MMDSQENYGS 910 920 930 940 950 960 SMGGPNRNVT VTQTPSSGDW GLPNSKAGRM EPMNSNSMGR PGGDYNTSLP RPALGGSIPT 970 980 990 1000 1010 1020 LPLRSNSIPG ARPVLQQQQQ MLQMRPGEIP MGMGANPYGQ AAASNQLGSW PDGMLSMEQV 1030 1040 1050 1060 1070 1080 SHGTQNRPLL RNSLDDLVGP PSNLEGQSDE RALLDQLHTL LSNTDATGLE EIDRALGIPE 1090 1100 1110 1120 1130 1140 LVNQGQALEP KQDAFQGQEA AVMMDQKAGL YGQTYPAQGP PMQGGFHLQG QSPSFNSMMN 1150 1160 1170 1180 1190 1200 QMNQQGNFPL QGMHPRANIM RPRTNTPKQL RMQLQQRLQG QQFLNQSRQA LELKMENPTA 1210 1220 1230 1240 1250 1260 GGAAVMRPMM QPQGFLNAQM VAQRSRELLS HHFRQQRVAM MMQQQQQQQQ QQQQQQQQQQ 1270 1280 1290 1300 1310 1320 QQQQQQQQQQ QTQAFSPPPN VTASPSMDGL LAGPTMPQAP PQQFPYQPNY GMGQQPDPAF 1330 1340 1350 1360 1370 1380 GRVSSPPNAM MSSRMGPSQN PMMQHPQAAS IYQSSEMKGW PSGNLARNSS FSQQQFAHQG 1390 1400 1410 NPAVYSMVHM NGSSGHMGQM NMNPMPMSGM PMGPDQKYC

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI22548.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC122547 mRNA. Translation: AAI22548.1.
IPI	IPI00220082.
UniGene	Hs.592142
3D structure databases
SMR	Q0IIN7. Positions 1045-1091.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000124151. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:7670. NCOA3.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q0IIN7.
Gene expression databases
ArrayExpress	Q0IIN7.
Bgee	Q0IIN7.
Family and domain databases
InterPro	IPR010011. DUF1518. IPR001092. HLH_basic. IPR014920. Nuc_rcpt_coact_Ncoa-typ. IPR017426. Nuclear_rcpt_coactivator. IPR000014. PAS. IPR013767. PAS_fold. IPR014935. SRC-1. [Graphical view]
Pfam	PF07469. DUF1518. 1 hit. PF00010. HLH. 1 hit. PF08815. Nuc_rec_co-act. 1 hit. PF00989. PAS. 1 hit. PF08832. SRC-1. 1 hit. [Graphical view]
PIRSF	PIRSF038181. Nuclear_receptor_coactivator. 1 hit.
SMART	SM00353. HLH. 1 hit. SM00091. PAS. 1 hit. [Graphical view]
PROSITE	PS50888. HLH. 1 hit. PS50112. PAS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0IIN7_HUMAN

Accession

Primary (citable) accession number: Q0IIN7

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	March 3, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)