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Q0II25

- POP7_BOVIN

UniProt

Q0II25 - POP7_BOVIN

Protein

Ribonuclease P protein subunit p20

Gene

POP7

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences By similarity.By similarity

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro
    2. ribonuclease P activity Source: UniProtKB-EC

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein subunit p20 (EC:3.1.26.5)
    Short name:
    RNaseP protein p20
    Gene namesi
    Name:POP7
    Synonyms:RPP20
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 25

    Subcellular locationi

    Nucleusnucleolus By similarity. Cytoplasm By similarity. Cytoplasmic granule By similarity
    Note: Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleolus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 140140Ribonuclease P protein subunit p20PRO_0000271034Add
    BLAST

    Interactioni

    Subunit structurei

    Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and SMN1. RPP20/POP7 is probably a dimer By similarity.By similarity

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000037068.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0II25.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone-like Alba family.Curated

    Phylogenomic databases

    eggNOGiNOG86230.
    GeneTreeiENSGT00510000048483.
    HOGENOMiHOG000253010.
    HOVERGENiHBG001490.
    InParanoidiQ0II25.
    KOiK14527.
    OMAiCTEIYIH.
    OrthoDBiEOG7N37FG.
    TreeFamiTF313948.

    Family and domain databases

    Gene3Di3.30.110.20. 1 hit.
    InterProiIPR002775. DNA/RNA-bd_Alba-like.
    IPR014612. RNase_P/MRP_p20.
    [Graphical view]
    PANTHERiPTHR15314. PTHR15314. 1 hit.
    PIRSFiPIRSF036572. RPP20. 1 hit.
    SUPFAMiSSF82704. SSF82704. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0II25-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAENRESRGT VEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA    50
    RCQKLLDGGA RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA 100
    NTSTVELVDE LEPETDSREP LTRIRNNSAI HIRVFRVTPK 140
    Length:140
    Mass (Da):15,707
    Last modified:October 3, 2006 - v1
    Checksum:i7E4E130FF44B6BB4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC122839 mRNA. Translation: AAI22840.1.
    RefSeqiNP_001069950.1. NM_001076482.2.
    XP_005225275.1. XM_005225218.1.
    XP_005225276.1. XM_005225219.1.
    XP_005225277.1. XM_005225220.1.
    UniGeneiBt.22841.

    Genome annotation databases

    EnsembliENSBTAT00000037231; ENSBTAP00000037068; ENSBTAG00000026248.
    GeneIDi617906.
    KEGGibta:617906.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC122839 mRNA. Translation: AAI22840.1 .
    RefSeqi NP_001069950.1. NM_001076482.2.
    XP_005225275.1. XM_005225218.1.
    XP_005225276.1. XM_005225219.1.
    XP_005225277.1. XM_005225220.1.
    UniGenei Bt.22841.

    3D structure databases

    ProteinModelPortali Q0II25.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000037068.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000037231 ; ENSBTAP00000037068 ; ENSBTAG00000026248 .
    GeneIDi 617906.
    KEGGi bta:617906.

    Organism-specific databases

    CTDi 10248.

    Phylogenomic databases

    eggNOGi NOG86230.
    GeneTreei ENSGT00510000048483.
    HOGENOMi HOG000253010.
    HOVERGENi HBG001490.
    InParanoidi Q0II25.
    KOi K14527.
    OMAi CTEIYIH.
    OrthoDBi EOG7N37FG.
    TreeFami TF313948.

    Miscellaneous databases

    NextBioi 20900895.

    Family and domain databases

    Gene3Di 3.30.110.20. 1 hit.
    InterProi IPR002775. DNA/RNA-bd_Alba-like.
    IPR014612. RNase_P/MRP_p20.
    [Graphical view ]
    PANTHERi PTHR15314. PTHR15314. 1 hit.
    PIRSFi PIRSF036572. RPP20. 1 hit.
    SUPFAMi SSF82704. SSF82704. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Hereford.
      Tissue: Hypothalamus.

    Entry informationi

    Entry nameiPOP7_BOVIN
    AccessioniPrimary (citable) accession number: Q0II25
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 9, 2007
    Last sequence update: October 3, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3