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Protein

Ribonuclease P protein subunit p20

Gene

POP7

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p20 (EC:3.1.26.5)
Short name:
RNaseP protein p20
Gene namesi
Name:POP7
Synonyms:RPP20
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Organism-specific databases

VGNCiVGNC:33166 POP7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002710341 – 140Ribonuclease P protein subunit p20Add BLAST140

Proteomic databases

PaxDbiQ0II25
PRIDEiQ0II25

Expressioni

Gene expression databases

BgeeiENSBTAG00000026248

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and SMN1. RPP20/POP7 is probably a dimer (By similarity).By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000037068

Structurei

3D structure databases

ProteinModelPortaliQ0II25
SMRiQ0II25
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like Alba family.Curated

Phylogenomic databases

eggNOGiENOG410IXMT Eukaryota
ENOG4111R36 LUCA
GeneTreeiENSGT00510000048483
HOGENOMiHOG000253010
HOVERGENiHBG001490
InParanoidiQ0II25
KOiK14527
OMAiGQNACTE
OrthoDBiEOG091G0Y8P
TreeFamiTF313948

Family and domain databases

Gene3Di3.30.110.20, 1 hit
InterProiView protein in InterPro
IPR036882 Alba-like_dom_sf
IPR014612 Pop7/Rpp20
PANTHERiPTHR15314 PTHR15314, 1 hit
PfamiView protein in Pfam
PF12328 Rpp20, 1 hit
PIRSFiPIRSF036572 RPP20, 1 hit
SUPFAMiSSF82704 SSF82704, 1 hit

Sequencei

Sequence statusi: Complete.

Q0II25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAENRESRGT VEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA
60 70 80 90 100
RCQKLLDGGA RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA
110 120 130 140
NTSTVELVDE LEPETDSREP LTRIRNNSAI HIRVFRVTPK
Length:140
Mass (Da):15,707
Last modified:October 3, 2006 - v1
Checksum:i7E4E130FF44B6BB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC122839 mRNA Translation: AAI22840.1
RefSeqiNP_001069950.1, NM_001076482.2
XP_005225275.1, XM_005225218.1
XP_005225276.1, XM_005225219.1
XP_015315985.1, XM_015460499.1
UniGeneiBt.22841

Genome annotation databases

EnsembliENSBTAT00000037231; ENSBTAP00000037068; ENSBTAG00000026248
GeneIDi617906
KEGGibta:617906

Similar proteinsi

Entry informationi

Entry nameiPOP7_BOVIN
AccessioniPrimary (citable) accession number: Q0II25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 3, 2006
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health