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Q0II25

- POP7_BOVIN

UniProt

Q0II25 - POP7_BOVIN

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Protein

Ribonuclease P protein subunit p20

Gene

POP7

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. poly(A) RNA binding Source: Ensembl
  2. ribonuclease P activity Source: UniProtKB-EC

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p20 (EC:3.1.26.5)
Short name:
RNaseP protein p20
Gene namesi
Name:POP7
Synonyms:RPP20
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 25

Subcellular locationi

Nucleusnucleolus By similarity. Cytoplasm By similarity. Cytoplasmic granule By similarity
Note: Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 140140Ribonuclease P protein subunit p20PRO_0000271034Add
BLAST

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and SMN1. RPP20/POP7 is probably a dimer (By similarity).By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000037068.

Structurei

3D structure databases

ProteinModelPortaliQ0II25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like Alba family.Curated

Phylogenomic databases

eggNOGiNOG86230.
GeneTreeiENSGT00510000048483.
HOGENOMiHOG000253010.
HOVERGENiHBG001490.
InParanoidiQ0II25.
KOiK14527.
OMAiCTEIYIH.
OrthoDBiEOG7N37FG.
TreeFamiTF313948.

Family and domain databases

Gene3Di3.30.110.20. 1 hit.
InterProiIPR002775. DNA/RNA-bd_Alba-like.
IPR014612. RNase_P/MRP_p20.
[Graphical view]
PANTHERiPTHR15314. PTHR15314. 1 hit.
PIRSFiPIRSF036572. RPP20. 1 hit.
SUPFAMiSSF82704. SSF82704. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0II25-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAENRESRGT VEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA
60 70 80 90 100
RCQKLLDGGA RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA
110 120 130 140
NTSTVELVDE LEPETDSREP LTRIRNNSAI HIRVFRVTPK
Length:140
Mass (Da):15,707
Last modified:October 3, 2006 - v1
Checksum:i7E4E130FF44B6BB4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC122839 mRNA. Translation: AAI22840.1.
RefSeqiNP_001069950.1. NM_001076482.2.
XP_005225275.1. XM_005225218.1.
XP_005225276.1. XM_005225219.1.
XP_005225277.1. XM_005225220.1.
UniGeneiBt.22841.

Genome annotation databases

EnsembliENSBTAT00000037231; ENSBTAP00000037068; ENSBTAG00000026248.
GeneIDi617906.
KEGGibta:617906.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC122839 mRNA. Translation: AAI22840.1 .
RefSeqi NP_001069950.1. NM_001076482.2.
XP_005225275.1. XM_005225218.1.
XP_005225276.1. XM_005225219.1.
XP_005225277.1. XM_005225220.1.
UniGenei Bt.22841.

3D structure databases

ProteinModelPortali Q0II25.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000037068.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000037231 ; ENSBTAP00000037068 ; ENSBTAG00000026248 .
GeneIDi 617906.
KEGGi bta:617906.

Organism-specific databases

CTDi 10248.

Phylogenomic databases

eggNOGi NOG86230.
GeneTreei ENSGT00510000048483.
HOGENOMi HOG000253010.
HOVERGENi HBG001490.
InParanoidi Q0II25.
KOi K14527.
OMAi CTEIYIH.
OrthoDBi EOG7N37FG.
TreeFami TF313948.

Miscellaneous databases

NextBioi 20900895.

Family and domain databases

Gene3Di 3.30.110.20. 1 hit.
InterProi IPR002775. DNA/RNA-bd_Alba-like.
IPR014612. RNase_P/MRP_p20.
[Graphical view ]
PANTHERi PTHR15314. PTHR15314. 1 hit.
PIRSFi PIRSF036572. RPP20. 1 hit.
SUPFAMi SSF82704. SSF82704. 1 hit.
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Hypothalamus.

Entry informationi

Entry nameiPOP7_BOVIN
AccessioniPrimary (citable) accession number: Q0II25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 3, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3