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Q0II25 (POP7_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein subunit p20

Short name=RNaseP protein p20
EC=3.1.26.5
Gene names
Name:POP7
Synonyms:RPP20
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length140 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences By similarity.

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Subunit structure

Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and SMN1. RPP20/POP7 is probably a dimer By similarity.

Subcellular location

Nucleusnucleolus By similarity. Cytoplasm By similarity. Cytoplasmic granule By similarity. Note: Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules By similarity.

Sequence similarities

Belongs to the histone-like Alba family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
Nucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 140140Ribonuclease P protein subunit p20
PRO_0000271034

Sequences

Sequence LengthMass (Da)Tools
Q0II25 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 7E4E130FF44B6BB4

FASTA14015,707
        10         20         30         40         50         60 
MAENRESRGT VEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA RCQKLLDGGA 

        70         80         90        100        110        120 
RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA NTSTVELVDE LEPETDSREP 

       130        140 
LTRIRNNSAI HIRVFRVTPK 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Hypothalamus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC122839 mRNA. Translation: AAI22840.1.
RefSeqNP_001069950.1. NM_001076482.2.
XP_005225275.1. XM_005225218.1.
XP_005225276.1. XM_005225219.1.
XP_005225277.1. XM_005225220.1.
UniGeneBt.22841.

3D structure databases

ProteinModelPortalQ0II25.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000037068.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000037231; ENSBTAP00000037068; ENSBTAG00000026248.
GeneID617906.
KEGGbta:617906.

Organism-specific databases

CTD10248.

Phylogenomic databases

eggNOGNOG86230.
GeneTreeENSGT00510000048483.
HOGENOMHOG000253010.
HOVERGENHBG001490.
InParanoidQ0II25.
KOK14527.
OMACTEIYIH.
OrthoDBEOG7N37FG.
TreeFamTF313948.

Family and domain databases

Gene3D3.30.110.20. 1 hit.
InterProIPR002775. DNA/RNA-bd_Alba-like.
IPR014612. RNase_P/MRP_p20.
[Graphical view]
PANTHERPTHR15314. PTHR15314. 1 hit.
PIRSFPIRSF036572. RPP20. 1 hit.
SUPFAMSSF82704. SSF82704. 1 hit.
ProtoNetSearch...

Other

NextBio20900895.

Entry information

Entry namePOP7_BOVIN
AccessionPrimary (citable) accession number: Q0II25
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 3, 2006
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families