Reviewed, UniProtKB/Swiss-Prot Q0IHQ9 (ACPL2_XENTR)

Names and origin

Protein names

Recommended name:
    Acid phosphatase-like protein 2
    EC=3.1.3.2

Gene names

Name:

acpl2

Organism

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Taxonomic identifier

8364 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Hydrolase
PTM	Glycoprotein
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 501	478	Acid phosphatase-like protein 2		PRO_0000314928
Sites
	Active site	120	1	Nucleophile By similarity
	Active site	402	1	Proton donor By similarity
Amino acid modifications
	Glycosylation	328	1	N-linked (GlcNAc...) Potential
	Glycosylation	377	1	N-linked (GlcNAc...) Potential
	Glycosylation	488	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q0IHQ9-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 92FB07C4CBF11B71	FASTA	501	57,977
	10 20 30 40 50 60 MLLRNRFLLL LALAGLLAFL SLSLQFFSRW LPVSLQLKTE MQVFPEFPVR LIQVGQGREE 70 80 90 100 110 120 GLGAKNRKRI MPEPLTEPPA LNPLYEANLY CNTPGAKERS MEGHAPPNLK LLSVQVIIRH 130 140 150 160 170 180 GDRYPLYTIP KTKRPDIDCV LEPGRKPSHP HLTDFISHMS KGVDTQMDGT LGSLPRLPNH 190 200 210 220 230 240 ILCEMGELTQ TGVVQHLRNG QLLKEIYLKK HRLLTSAWTA KHLYFESTGK SRTLQSGLAL 250 260 270 280 290 300 LYSLLPNFDW KKINVKHQWS TIFCSNHCDC PMRNHYLEEE QRRQYNFRVK NSLLEKTYIN 310 320 330 340 350 360 MAKIVGIPTR QLRASNPIDS LLCNFCHNAT FPCTKNGCID LEHFKVIKTH QLEDEKERYE 370 380 390 400 410 420 KQLYFKYALM ATHPLLNQTA NRMLRIAEGK KDELFALYSA HDVTLSPILS ALGLREARFP 430 440 450 460 470 480 RFAARLVFEL WHDPEKANNH YVRVLYNGED VTFQTSFCRD QLRSSKRPLC PLKKFSTFVQ 490 500 KDMFSSLNST SYYDACHQRL F

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC123016 mRNA. Translation: AAI23017.1.
RefSeq	NP_001072621.1.
UniGene	Str.65007
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	780077.
KEGG	xtr:780077.
Organism-specific databases
CTD	780077.
Xenbase	XB-FEAT-979575. acpl2.
Phylogenomic databases
HOVERGEN	Q0IHQ9.
Enzyme and pathway databases
BRENDA	3.1.3.2. 279072.
Family and domain databases
InterPro	IPR000560. Histidine_acid_Pase. [Graphical view]
Pfam	PF00328. Acid_phosphat_A. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACPL2_XENTR

Accession

Primary (citable) accession number: Q0IHQ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	September 1, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Xenopus annotation project