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Protein

N-alpha-acetyltransferase 30

Gene

naa30

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly (By similarity).By similarity

Catalytic activityi

Acetyl-CoA + peptide = N(alpha)-acetylpeptide + CoA.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
N-alpha-acetyltransferase 30 (EC:2.3.1.88)
Alternative name(s):
N-acetyltransferase 12
N-acetyltransferase MAK3 homolog
NatC catalytic subunit
Gene namesi
Name:naa30
Synonyms:mak3, nat12
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-877045. naa30.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003200341 – 273N-alpha-acetyltransferase 30Add BLAST273

Interactioni

Subunit structurei

Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of naa35, naa38 and naa30.By similarity

Protein-protein interaction databases

BioGridi607929. 1 interactor.
IntActiQ0IHH1. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ0IHH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 273N-acetyltransferasePROSITE-ProRule annotationAdd BLAST149

Sequence similaritiesi

Contains 1 N-acetyltransferase domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG082671.
KOiK00670.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0IHH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADAPSGPSV LSHYPGAGLA GEQQREEERH KGCHHHQLNG LISPDLRHLK
60 70 80 90 100
AVSSLKNKLL EQKTRKDSGL VQPQGRTDTR APNGLERLQG EEEKLSACLA
110 120 130 140 150
SCSLRGDGEA LGNHVSQGEN DDTIRYVRYE SELQMADIMR LITRDLSEPY
160 170 180 190 200
SIYTYRYFIH NWPQLCFLAM VGEECVGAIV CKLDMHKKMF RRGYIAMLAV
210 220 230 240 250
DSKYRRKGIG THLVKKAIYA MVEGDCDEVV LETEITNKSA LKLYENLGFV
260 270
RDKRLFRYYL NGVDALRLKL WLR
Length:273
Mass (Da):31,074
Last modified:October 3, 2006 - v1
Checksum:iD5D916DD6A7B90ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC123156 mRNA. Translation: AAI23157.1.
RefSeqiNP_001090313.1. NM_001096844.1.
UniGeneiXl.59924.

Genome annotation databases

GeneIDi779222.
KEGGixla:779222.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC123156 mRNA. Translation: AAI23157.1.
RefSeqiNP_001090313.1. NM_001096844.1.
UniGeneiXl.59924.

3D structure databases

ProteinModelPortaliQ0IHH1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi607929. 1 interactor.
IntActiQ0IHH1. 1 interactor.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi779222.
KEGGixla:779222.

Organism-specific databases

CTDi122830.
XenbaseiXB-GENE-877045. naa30.

Phylogenomic databases

HOVERGENiHBG082671.
KOiK00670.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNAA30_XENLA
AccessioniPrimary (citable) accession number: Q0IHH1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 3, 2006
Last modified: May 11, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.