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Q0ID96 (PYRB_SYNS3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate carbamoyltransferase

EC=2.1.3.2
Alternative name(s):
Aspartate transcarbamylase
Short name=ATCase
Gene names
Name:pyrB
Ordered Locus Names:sync_0343
OrganismSynechococcus sp. (strain CC9311) [Complete proteome] [HAMAP]
Taxonomic identifier64471 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP-Rule MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP-Rule MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 349349Aspartate carbamoyltransferase HAMAP-Rule MF_00001
PRO_0000301632

Sequences

Sequence LengthMass (Da)Tools
Q0ID96 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 7A59A091FD1C2CA9

FASTA34937,879
        10         20         30         40         50         60 
MSGWSHRHVL DLASFSRDDY ATVLELAHRF RSMPVTGARK LPALQGRLVA TLFFEPSTRT 

        70         80         90        100        110        120 
RSSFELAAKR LSADVQSFSP SSSSLSKGES LLDTARTYVA MGADVLVIRH RCTDVPAQLA 

       130        140        150        160        170        180 
SELDQAGERT VVLNGGDGQH SHPSQGLLDL YTLAHHFDPR NSQLDALQGK RIVIVGDVVH 

       190        200        210        220        230        240 
SRVARSNLWA LSACGADVVL CGPPSLVPDA FAAFLDAPPP GQASDPVRER GTVQISRSLD 

       250        260        270        280        290        300 
DCLSGADAVM TLRLQKERMT DHLLTNLDRY HRDFGLTHER LRRCAFSGPV LHPGPVNRGV 

       310        320        330        340 
EMSGGLLDDR SICLVEDQVR NGIPIRMALL YLMAASDPVA ESSRASAPS 

« Hide

References

[1]"Genome sequence of Synechococcus CC9311: insights into adaptation to a coastal environment."
Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H., Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S., Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R., Paulsen I.T.
Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9311.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000435 Genomic DNA. Translation: ABI46806.1.
RefSeqYP_729576.1. NC_008319.1.

3D structure databases

ProteinModelPortalQ0ID96.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING64471.sync_0343.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI46806; ABI46806; sync_0343.
GeneID4258954.
KEGGsyg:sync_0343.
PATRIC23791540. VBISynSp88089_0351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0540.
HOGENOMHOG000022685.
KOK00609.
OMAMTLNAMR.
OrthoDBEOG61KBJZ.

Enzyme and pathway databases

BioCycSSP64471:GIVP-343-MONOMER.
UniPathwayUPA00070; UER00116.

Family and domain databases

Gene3D3.40.50.1370. 2 hits.
HAMAPMF_00001. Asp_carb_tr.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMSSF53671. SSF53671. 1 hit.
TIGRFAMsTIGR00670. asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRB_SYNS3
AccessionPrimary (citable) accession number: Q0ID96
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 3, 2006
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways