Q0I8U7 (Q0I8U7_SYNS3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotase, homodimeric type EMBL ABI46962.1
EC=3.5.2.3 EMBL ABI46962.1

Gene names

Name:	pyrC EMBL ABI46962.1
Ordered Locus Names:	sync_1922

Organism

Synechococcus sp. (strain CC9311) [Complete proteome] [HAMAP] EMBL ABI46962.1

Taxonomic identifier

64471 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	370 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. SAAS SAAS004721
Cofactor	Binds 2 zinc ions per subunit By similarity. SAAS SAAS004721
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. SAAS SAAS004721
Subunit structure	Homodimer By similarity. SAAS SAAS004721

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis SAAS SAAS004721
Ligand	Metal-binding SAAS SAAS004721 Zinc SAAS SAAS004721
Molecular function	Hydrolase SAAS SAAS004721 EMBL ABI46962.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	dihydroorotase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0I8U7 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 2E9EC1B49FE7269D	FASTA	370	41,008
	10 20 30 40 50 60 MTSSDRLVLR RPDDWHVHLR DGAMLKAVLP ATARTFARAI VMPNLRPPVT SVEEAVAYRA 70 80 90 100 110 120 RILAALPEGV SFQPLMTAYL TDAIDPWELD RGFHQGVFSA AKLYPANATT NSAAGVSDLQ 130 140 150 160 170 180 NISAVLERME AIDMPLLIHG EVTDPDVDVF DREALFIQRH LKPLRERHPR LRIILEHITT 190 200 210 220 230 240 EEAVTYIRDS YQGGDERIAA TITPHHLHLN RNAMFVGGLR SDFYCLPVVK RECHRRALVQ 250 260 270 280 290 300 AATSGLPCFF LGTDSAPHPR SGKESACGCA GIFNAFHALE SYATVFEQEG ALDRLEGFAS 310 320 330 340 350 360 EYGPHFYGLS LNTDTVTLVR RDQPIPSRLL PPHSARSGDD TLPESEWPLL FHAGETLAWC 370 VEMNGHSGAN

References

[1]

"Genome sequence of Synechococcus CC9311: insights into adaptation to a coastal environment." Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H., Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S., Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R., Paulsen I.T. Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006) [PubMed: 16938853] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000435 Genomic DNA. Translation: ABI46962.1.
RefSeq	YP_731125.1. NC_008319.1.
3D structure databases
ProteinModelPortal	Q0I8U7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0I8U7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4260442.
GenomeReviews	Gene locus sync_1922 in contig CP000435_GR.
KEGG	syg:sync_1922.
PATRIC	23794910. VBISynSp88089_2010.
TIGR	sync_1922.
Phylogenomic databases
eggNOG	COG0418.
HOGENOM	HBG628648.
OMA	CLPVAKR.
PhylomeDB	Q0I8U7.
ProtClustDB	PRK05451.
Family and domain databases
HAMAP	MF_00219. PyrC_type1. [Tree]
InterPro	IPR006680. Amidohydro_1. IPR004721. DHOdimr. IPR002195. Dihydroorotase_CS. [Graphical view]
KO	K01465.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
PIRSF	PIRSF001237. DHOdimr. 1 hit.
TIGRFAMs	TIGR00856. PyrC_dimer. 1 hit.
PROSITE	PS00482. DIHYDROOROTASE_1. 1 hit. PS00483. DIHYDROOROTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0I8U7_SYNS3

Accession

Primary (citable) accession number: Q0I8U7

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)