Q0I8H5 (PHS_SYNS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

sync_2044

Organism

Synechococcus sp. (strain CC9311) [Complete proteome] [HAMAP]

Taxonomic identifier

64471 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	99 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 99	99	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000050467

Sequences

	Sequence		Length	Mass (Da)
	Q0I8H5 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: AF81DF02FE9DDD56	FASTA	99	11,049
	10 20 30 40 50 60 MSKQAVLLDE AARQSLYSSC PAWTIASDGL VREWRFHSFV EAFGFMTQVA LLAERANHHP 70 80 90 EWSNVYNRVT IRLTTHDLGG LSSRDAELAQ AIDSLSPTT

References

[1]

"Genome sequence of Synechococcus CC9311: insights into adaptation to a coastal environment." Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H., Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S., Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R., Paulsen I.T. Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006) [PubMed: 16938853] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9311.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000435 Genomic DNA. Translation: ABI45298.1.
RefSeq	YP_731247.1. NC_008319.1.
3D structure databases
ProteinModelPortal	Q0I8H5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0I8H5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4261236.
GenomeReviews	Gene locus sync_2044 in contig CP000435_GR.
KEGG	syg:sync_2044.
PATRIC	23795164. VBISynSp88089_2137.
TIGR	sync_2044.
Phylogenomic databases
eggNOG	COG2154.
HOGENOM	HBG705804.
OMA	IALICEK.
PhylomeDB	Q0I8H5.
ProtClustDB	PRK00823.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_SYNS3

Accession

Primary (citable) accession number: Q0I8H5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program