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Q0I6R7 (SYR_SYNS3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:sync_2667
OrganismSynechococcus sp. (strain CC9311) [Complete proteome] [HAMAP]
Taxonomic identifier64471 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length590 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 590590Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018138

Regions

Motif130 – 14011"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q0I6R7 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 7D4D1249747B8C66

FASTA59065,145
        10         20         30         40         50         60 
MLRIAQALDT QLREAMQRAF PDVDALLDPQ LAPANKPEFG DFQANGALPL AKPLKQAPRL 

        70         80         90        100        110        120 
IAGAIVEALQ ADPAFAALCL EPQIAGPGFI NLTIRPERLA AEVSARLGDP RLGVPEVQSD 

       130        140        150        160        170        180 
AAVVVDFSSP NIAKEMHVGH LRSTIIGDSL ARVLEFRGHR VLRLNHVGDW GTQFGMLITH 

       190        200        210        220        230        240 
LKQVAPETLN RADAVDLGDL VAFYREAKKR FDEDEAFQAT SREEVVKLQG GDPVSLKAWG 

       250        260        270        280        290        300 
LLCDQSRREF QKIYDRLDIR LSERGESFYN PYLASVLSGL KEADLLVTDD GAECVFLEGV 

       310        320        330        340        350        360 
NGKDGKPLPV IVRKSDGGFN YATTDLAAIR YRFALAPDGD GARRVIYVTD AGQANHFAGV 

       370        380        390        400        410        420 
FQVAKRANWI PEHGRLEHVP FGLVQGEDGK KLKTRSGDTV RLRDLLDEAV ERAEADLRRR 

       430        440        450        460        470        480 
LEEEGRSEDD QFIEHVAGTV GLAAVKYADL SQNRITNYQF SFDRMLALQG NTAPYLLYAV 

       490        500        510        520        530        540 
VRIAGIARKG GDLEAEAGML QFSEPQEWSL VRELLKFDAV IAEVEEELLP NRLCSYLFEL 

       550        560        570        580        590 
SQVFNRFYDQ VPVLKAEGQS LPSRLALCRL TADTLKSGLG LLGIATLERM 

« Hide

References

[1]"Genome sequence of Synechococcus CC9311: insights into adaptation to a coastal environment."
Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H., Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S., Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R., Paulsen I.T.
Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9311.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000435 Genomic DNA. Translation: ABI47463.1.
RefSeqYP_731855.1. NC_008319.1.

3D structure databases

ProteinModelPortalQ0I6R7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING64471.sync_2667.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI47463; ABI47463; sync_2667.
GeneID4259922.
KEGGsyg:sync_2667.
PATRIC23796456. VBISynSp88089_2769.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSSP64471:GIVP-2668-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNS3
AccessionPrimary (citable) accession number: Q0I6R7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries