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Q0I6M5

- PGK_SYNS3

UniProt

Q0I6M5 - PGK_SYNS3

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Synechococcus sp. (strain CC9311)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei122 – 1221SubstrateUniRule annotation
Binding sitei155 – 1551SubstrateUniRule annotation
Binding sitei206 – 2061ATPUniRule annotation
Binding sitei297 – 2971ATP; via carbonyl oxygenUniRule annotation
Binding sitei328 – 3281ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP64471:GIVP-2710-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:sync_2709
OrganismiSynechococcus sp. (strain CC9311)
Taxonomic identifieri64471 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000001961: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Phosphoglycerate kinasePRO_1000058081Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi64471.sync_2709.

Structurei

3D structure databases

ProteinModelPortaliQ0I6M5.
SMRiQ0I6M5. Positions 13-400.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni63 – 664Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0I6M5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKRSLAKLN TSDLSGKRVL VRVDFNVPLN DAGAITDDTR IRAALPTIND
60 70 80 90 100
LIGKGAKVIL AAHFGRPKGQ VNDKMRLTPV ATRLSELLSK PVTKTESCIG
110 120 130 140 150
PDAEAKVNAM ANGDVVLLEN VRFFAEEEKN DADFAKQLAG LADVYVNDAF
160 170 180 190 200
GAAHRAHAST EGVTKFLKPS VAGFLMEKEL QYLQGAVDEP KRPLAAIVGG
210 220 230 240 250
SKVSSKIGVL EALIDKCDKV LIGGGMIFTF YKARGLAVGK SLVEEDKLEL
260 270 280 290 300
AKELEAKAKA KGVELLLPTD VLLADNFAPD ANSQVADVTA IPDGWMGLDI
310 320 330 340 350
GPDAIKVFQA ALADCKTVIW NGPMGVFEFD KFAAGTNAIA TTLAELSGKG
360 370 380 390 400
CCTIIGGGDS VAAVEKAGLA EKMSHISTGG GASLELLEGK VLPGVAALDD

AA
Length:402
Mass (Da):42,028
Last modified:October 3, 2006 - v1
Checksum:iDD046454805F2657
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000435 Genomic DNA. Translation: ABI46222.1.
RefSeqiWP_011620601.1. NC_008319.1.
YP_731897.1. NC_008319.1.

Genome annotation databases

EnsemblBacteriaiABI46222; ABI46222; sync_2709.
GeneIDi4260066.
KEGGisyg:sync_2709.
PATRICi23796548. VBISynSp88089_2815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000435 Genomic DNA. Translation: ABI46222.1 .
RefSeqi WP_011620601.1. NC_008319.1.
YP_731897.1. NC_008319.1.

3D structure databases

ProteinModelPortali Q0I6M5.
SMRi Q0I6M5. Positions 13-400.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 64471.sync_2709.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI46222 ; ABI46222 ; sync_2709 .
GeneIDi 4260066.
KEGGi syg:sync_2709.
PATRICi 23796548. VBISynSp88089_2815.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci SSP64471:GIVP-2710-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CC9311.

Entry informationi

Entry nameiPGK_SYNS3
AccessioniPrimary (citable) accession number: Q0I6M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 3, 2006
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3