ID   SDHD_HAES1              Reviewed;         438 AA.
AC   Q0I5V1;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Probable D-serine dehydratase;
DE            EC=4.3.1.18;
DE   AltName: Full=D-serine deaminase;
DE            Short=DSD;
GN   Name=dsdA; OrderedLocusNames=HS_1718;
OS   Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17172329; DOI=10.1128/JB.01422-06;
RA   Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O.,
RA   Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N.,
RA   Xie G., Inzana T.J.;
RT   "Complete genome sequence of Haemophilus somnus (Histophilus somni)
RT   strain 129Pt and comparison to Haemophilus ducreyi 35000HP and
RT   Haemophilus influenzae Rd.";
RL   J. Bacteriol. 189:1890-1898(2007).
CC   -!- CATALYTIC ACTIVITY: D-serine = pyruvate + NH(3).
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- SIMILARITY: Belongs to the serine/threonine dehydratase family.
CC       DsdA subfamily.
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DR   EMBL; CP000436; ABI25986.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_719923.1; -.
DR   GeneID; 4241250; -.
DR   GenomeReviews; CP000436_GR; HS_1718.
DR   KEGG; hso:HS_1718; -.
DR   NMPDR; fig|205914.1.peg.1659; -.
DR   HOGENOM; Q0I5V1; -.
DR   BioCyc; HSOM205914:HS_1718-MON; -.
DR   GO; GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:HAMAP.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0046416; P:D-amino acid metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01030; -; 1.
DR   InterPro; IPR011780; D_Ser_am_lyase.
DR   InterPro; IPR001926; PyrdxlP-dep_enz_bsu.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   PANTHER; PTHR10314:SF9; D_Ser_am_lyase; 1.
DR   Pfam; PF00291; PALP; 1.
DR   TIGRFAMs; TIGR02035; D_Ser_am_lyase; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase; Pyridoxal phosphate.
FT   CHAIN         1    438       Probable D-serine dehydratase.
FT                                /FTId=PRO_0000291732.
FT   MOD_RES     114    114       N6-(pyridoxal phosphate)lysine (By
FT                                similarity).
SQ   SEQUENCE   438 AA;  48558 MW;  DEB359375D95687C CRC64;
     MKIQHLMQDP FIQKLMRFEE VMWFNPKSAG VKTGLSYVGL DVSDTQQAAE RLQRFAPYFC
     RAFPETQKTK GILESELVSI DKMKSALIDH YHMPIQGRLL LKKDSHLPIS GSIKARGGIY
     EVLAYAEKLA LEHHLITEND DYSQLCDEKI KDFFSRYSIA VGSTGNLGLS IGIMGAVLGF
     KVSVHMSADA REWKKQKLRS YGVNVVEYTQ DYGVAVAQGR KAALSDPNCF FIDDENSTTL
     FLGYSVAGQR LKQQFLEQGI KVDENHPLFV YLPCGVGGGP GGVAFGLKLA FGDYVHCIFA
     EPTHSPCMLL GVYTGLHDKI AVQDLGIDNI TAADGLAVGR ASGFVGRAME HLLDGFYTIE
     DQKLYDLLGL LHKTENIQLE PSALAGMIGP LHINHSDYLR RYHITQEQLA NATHIVWATG
     GGMVPDVEMQ KYLSLGRF
//