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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Haemophilus somnus (strain 129Pt) (Histophilus somni)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:HS_1558
OrganismiHaemophilus somnus (strain 129Pt) (Histophilus somni)
Taxonomic identifieri205914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
Proteomesi
  • UP000001970 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120641 – 273Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST273

Interactioni

Protein-protein interaction databases

STRINGi205914.HS_1558

Structurei

3D structure databases

ProteinModelPortaliQ0I5C4
SMRiQ0I5C4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q0I5C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYLVGDLQ GCYDELQLLL ETVQFNPVQD KLYLVGDLVA RGDKSLECLR
60 70 80 90 100
FVKSLGAAAQ MVLGNHDLHL ISTALGIKKV SLQDHVEAIF TAPDFVELID
110 120 130 140 150
WLRHQPLLVH DEKCDFVMSH AGISPDWDLD TAKSCAREVE NELQHGDYHY
160 170 180 190 200
LISNMYDNQP DRWSADLQGL QRLRYSINVF TRMRFCYRDH RLDFACKASV
210 220 230 240 250
EKASQELIPW FNLDNPLFKV QNLVFGHWAS LVDTPTPANI YALDTGCVWG
260 270
NRMTMLRWED KQYFVQGALK DYF
Length:273
Mass (Da):31,455
Last modified:October 3, 2006 - v1
Checksum:i2FE9D61E68CEC62F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000436 Genomic DNA Translation: ABI25826.1
RefSeqiWP_011609704.1, NC_008309.1

Genome annotation databases

EnsemblBacteriaiABI25826; ABI25826; HS_1558
KEGGihso:HS_1558

Similar proteinsi

Entry informationi

Entry nameiAPAH_HAES1
AccessioniPrimary (citable) accession number: Q0I5C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health