Reviewed, UniProtKB/Swiss-Prot Q0I4V7 (SYK3_HAES1)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	HS_1276

Organism

Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)) [Complete proteome] [HAMAP]

Taxonomic identifier

205914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Histophilus

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000023625

Sequences

	Sequence		Length	Mass (Da)
	Q0I4V7-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 891B7D8848B20F22	FASTA	323	36,724
	10 20 30 40 50 60 MSLNEQWQPS ASIQNLLARA KIIADIRRFF TERGLLEVET PVLSEFGVTD VHLSTFSTAF 70 80 90 100 110 120 TSPFMEKSKT LWLTTSPEYH MKRLLAAGSG AIFQLCKVFR NEESGKKHNP EFTMLEWYRP 130 140 150 160 170 180 HFDMHRLINE VDDLLQQTLD CEPAEMASYQ FVFQEHVGID PLSAPINELI EKARECHLDG 190 200 210 220 230 240 AENEDRDTLL QFLFSTLVEP NIGQNKPIAV YHFPATQAAL AQISSEDHRV AERFEFYYKG 250 260 270 280 290 300 IELANGFNEL TDAQEQEHRF NQDNRLREQL GLPQHEIDHR FLGALQAGLP NTAGVALGVD 310 320 RLIMLALGAE NISEVISFNI DCA

References

[1]

"Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd." Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J. J. Bacteriol. 189:1890-1898(2007) [PubMed: 17172329] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000436 Genomic DNA. Translation: ABI25551.1.
RefSeq	YP_719488.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4240787.
GenomeReviews	Gene locus HS_1276 in contig CP000436_GR.
KEGG	hso:HS_1276.
NMPDR	fig|205914.1.peg.890.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0I4V7.
OMA	Q0I4V7. VFRNEEA.
Enzyme and pathway databases
BioCyc	HSOM205914:HS_1276-MON.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_HAES1

Accession

Primary (citable) accession number: Q0I4V7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)