Q0I3R3 (ACKA_HAES1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	HS_0803

Organism

Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)) [Complete proteome] [HAMAP]

Taxonomic identifier

205914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Histophilus

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Acetate kinase HAMAP MF_00020		PRO_1000002236

Sequences

	Sequence		Length	Mass (Da)
	Q0I3R3 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 4490CBFE4740B18D	FASTA	398	43,303
	10 20 30 40 50 60 MSQKLVLILN CGSSSLKFAI LDPVSGAEKL SGLAEAFYLP DARIKWKLNG EKGNADLGAG 70 80 90 100 110 120 AAHSEALNFI VSTILTEDLK NSIAAIGHRV VHGGEKYTKS VVITDEVIQG IKDAAEFAPL 130 140 150 160 170 180 HNPAHLIGIE EAFKAFPHLK DNNVAIFDTA FHQTMPEEAF LYALPYSLYK EHGVRRYGMH 190 200 210 220 230 240 GTSHYFVSRE AAKRLNIAED KINVITCHLG NGASVAAIRQ GKCIDTSMGF TPLEGLVMGT 250 260 270 280 290 300 RSGDLDPAII FYMHNTLGMS VAQIEETLVK KSGLLGLTEV TSDCRYSEDN YEKESAAKRA 310 320 330 340 350 360 LDVFCYRLAK YIGSYMAIIG ENLDAIVFTG GIGENAALVR QITLNHLKLF GYKIDDEKNS 370 380 390 AARFGNEGVI TADNTPIAIV IPTNEELVIA QDTARLSF

References

[1]

"Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd." Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J. J. Bacteriol. 189:1890-1898(2007) [PubMed: 17172329] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 129Pt.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000436 Genomic DNA. Translation: ABI25078.1.
RefSeq	YP_719013.1. NC_008309.1.
3D structure databases
ProteinModelPortal	Q0I3R3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0I3R3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4240294.
GenomeReviews	Gene locus HS_0803 in contig CP000436_GR.
KEGG	hso:HS_0803.
NMPDR	fig|205914.1.peg.316.
PATRIC	20281613. VBIHaeSom53361_0844.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	ELMIVED.
PhylomeDB	Q0I3R3.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	HSOM205914:HS_0803-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_HAES1

Accession

Primary (citable) accession number: Q0I3R3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program