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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

sucA

Organism
Histophilus somni (strain 129Pt) (Haemophilus somnus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciHSOM205914:GJ7V-993-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
Name:sucAImported
Ordered Locus Names:HS_0959Imported
OrganismiHistophilus somni (strain 129Pt) (Haemophilus somnus)Imported
Taxonomic identifieri205914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
ProteomesiUP000001970 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi205914.HS_0959.

Structurei

3D structure databases

ProteinModelPortaliQ0I3A6.
SMRiQ0I3A6. Positions 82-930.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0I3A6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKNSPISEW LASSALGGAN QSYVEDLYED YLDNPQAVDE SWQQVFNSLP
60 70 80 90 100
KQNALEQPHS KVRDYFKRLA RDTSQNGVGV IDPNVSARLV NVLKWINGHR
110 120 130 140 150
NRGHLHADLD PLKMWQRMEA PTLDYKFYGF SDNDLDEVFD IGGYVYNKEQ
160 170 180 190 200
ISLRDLADSL KKTYCSTIGL EFMHVNDLDA RTWLQRKVER LLDKPLFTRE
210 220 230 240 250
EQLKFLEELI AADGLERYLG AKFPGAKRFS LEGSDAFILL MKEMIRHSSR
260 270 280 290 300
NGVKEIVMGM AHRGRLNLLV NVLGKKPSEL FDEFAGKHSG SGTGDVKYHQ
310 320 330 340 350
GFSSDFMTDD GIVHLALAFN PSHLEIVNPV VLGSVRARQN RIQDVERSQV
360 370 380 390 400
LPITVHGDSA VAGQGIVQET LNMSEVRGYT VGGTIRVVIN NQIGFTTSNL
410 420 430 440 450
QDTRSTEYCT DIAKMIEAPV IHVNGDDPEA VAYAARMAVE FRAKFKRDIF
460 470 480 490 500
IDLVSYRRHG HNEADEPAVT QPLMYERIRK HPTPPKVYTN RLVTEGIIDE
510 520 530 540 550
AYAIELANKY RDALDNGGCV VPEWREADIE TKDWTKYLTQ EWTEYDGSFD
560 570 580 590 600
SERFVGLAKK VCDYPSSHSL HPRVKKLYDD RLSMAQGDKL FDWGMAETMA
610 620 630 640 650
YATLLDEGYN VRLSGEDAGR GTFFHRHSVL HNQKDATLYI PLTQLHAQQG
660 670 680 690 700
RFEVWDSVLS EEAVLAYEYG YATAAPRTLT IWEAQFGDFA NVAQVVIDQF
710 720 730 740 750
ISSGEQKWGR MCGLVMLLPH GYEGQGPEHS SARLERYLQL CAQQNMQVCV
760 770 780 790 800
PSTPAQIYHL LRRQMLRKVR RPLVVITPKS LLRRPLVVST MEELIHGKYQ
810 820 830 840 850
NVIAEIDAID PQKVRRVVMC SGKVYYDLLE QRRENNQMDV AIIRIEQLYP
860 870 880 890 900
YPHEEMKEAL APYSHVTDYV WCQEEPLNQG AWYCCQHNFW TSLPPHGKLR
910 920 930
YVGRPASASP AVGYLSLHNE QQRALVTEAL A
Length:931
Mass (Da):106,010
Last modified:October 3, 2006 - v1
Checksum:iA50F155829E93408
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000436 Genomic DNA. Translation: ABI25234.1.
RefSeqiWP_011609113.1. NC_008309.1.
YP_719170.1. NC_008309.1.

Genome annotation databases

EnsemblBacteriaiABI25234; ABI25234; HS_0959.
KEGGihso:HS_0959.
PATRICi20281937. VBIHaeSom53361_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000436 Genomic DNA. Translation: ABI25234.1.
RefSeqiWP_011609113.1. NC_008309.1.
YP_719170.1. NC_008309.1.

3D structure databases

ProteinModelPortaliQ0I3A6.
SMRiQ0I3A6. Positions 82-930.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi205914.HS_0959.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI25234; ABI25234; HS_0959.
KEGGihso:HS_0959.
PATRICi20281937. VBIHaeSom53361_1005.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciHSOM205914:GJ7V-993-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd."
    Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J.
    J. Bacteriol. 189:1890-1898(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 129PtImported.

Entry informationi

Entry nameiQ0I3A6_HISS1
AccessioniPrimary (citable) accession number: Q0I3A6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: April 1, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.