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Q0I371 (CAPP_HISS1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:HS_0994
OrganismHistophilus somni (strain 129Pt) (Haemophilus somnus) [Complete proteome] [HAMAP]
Taxonomic identifier205914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus

Protein attributes

Sequence length879 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 879879Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025562

Sites

Active site1381 By similarity
Active site5451 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0I371 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 9168FEAF95757797

FASTA87999,900
        10         20         30         40         50         60 
MPQKYSTLKN NINMLGHFLG ETISDAQGSD ILDLIENIRV LSRDSRSGDE KAREKLLDTL 

        70         80         90        100        110        120 
STISNENIIP VARAFSQFLN LTNIAEQYQT ISRKHIDQVA SDRSLEALFE RLKAQNVPAE 

       130        140        150        160        170        180 
KVISTVEKLL IELVLTAHPT EVTRRSLLHK YVEINRCLSR LEHDDLTQSE STKLKRRLMQ 

       190        200        210        220        230        240 
LIALAWHTNE IRTQRPTPVD EAKWGIAVIE NSLWKAVPDF CRQLNLHLEK NFGVQHSVNL 

       250        260        270        280        290        300 
APVKFSSWIG GDRDGNPFVT AETTRQVLIM NRWKAAELFL ADIQVLSEEL SVVHCTEEFR 

       310        320        330        340        350        360 
AKYGDHLEPY RVVVKNLRAK LVKTVAYYGE ILENKPSTIN TNDILTDDQQ LWEPLYDCYQ 

       370        380        390        400        410        420 
SLHQCGMRII ANGILLDCLR RIRCFGLSLS HLDIRQESLR HTKALSEITR YIGLGDYSQW 

       430        440        450        460        470        480 
MEDDKQAFLI RELSSRRPLL PRNWTPSLET QEILETCRVI AQQPEGVISC YIISMARTAS 

       490        500        510        520        530        540 
DVLAVHLLLK EAGVTYYLPV VPLFETLDDL NASKEVMTQL FNVGWYRGVI NNKQMVMIGY 

       550        560        570        580        590        600 
SDSAKDAGMM AASWAQYRAQ EQLVNLCEKM GVELTLFHGR GGTIGRGGAP AHAALLSQPP 

       610        620        630        640        650        660 
RSLKNGLRVT EQGEMIRFKL GLPAVAVNSF DLYASAILEA NLLPPPEPKE SWRAIMNELS 

       670        680        690        700        710        720 
DSSCNIYRSV VRGDKDFVPY FRSATPEQEL SKLPLGSRPS KRNPNGGVES LRAIPWIFAW 

       730        740        750        760        770        780 
MQNRLMLPAW LGASASIRQS IEKGNKETIE EMCKNWPFFS TRIGMLEMVF SKTDTWLSEH 

       790        800        810        820        830        840 
YDLNLVKKEL WYLGQSLREQ LQADIKTILS LSHEDELMSD LPWIAESIAL RNIYTDPLNL 

       850        860        870 
LQVELLRRLR ENPENPNPDV EQALMITITG IAAGMRNTG 

« Hide

References

[1]"Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd."
Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J.
J. Bacteriol. 189:1890-1898(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 129Pt.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000436 Genomic DNA. Translation: ABI25269.1.
RefSeqYP_719205.1. NC_008309.1.

3D structure databases

ProteinModelPortalQ0I371.
SMRQ0I371. Positions 4-879.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING205914.HS_0994.

Proteomic databases

PRIDEQ0I371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI25269; ABI25269; HS_0994.
GeneID4240487.
KEGGhso:HS_0994.
PATRIC20282011. VBIHaeSom53361_1042.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycHSOM205914:GJ7V-1028-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_HISS1
AccessionPrimary (citable) accession number: Q0I371
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families