ID   URK_HAES1               Reviewed;         213 AA.
AC   Q0I2Y9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Uridine kinase;
DE            EC=2.7.1.48;
DE   AltName: Full=Uridine monophosphokinase;
DE   AltName: Full=Cytidine monophosphokinase;
GN   Name=udk; OrderedLocusNames=HS_0644;
OS   Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17172329; DOI=10.1128/JB.01422-06;
RA   Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O.,
RA   Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N.,
RA   Xie G., Inzana T.J.;
RT   "Complete genome sequence of Haemophilus somnus (Histophilus somni)
RT   strain 129Pt and comparison to Haemophilus ducreyi 35000HP and
RT   Haemophilus influenzae Rd.";
RL   J. Bacteriol. 189:1890-1898(2007).
CC   -!- CATALYTIC ACTIVITY: ATP + uridine = ADP + UMP.
CC   -!- CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.
CC   -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage
CC       pathway; CTP from cytidine: step 1/3.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage
CC       pathway; UMP from uridine: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the uridine kinase family.
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DR   EMBL; CP000436; ABI24921.1; -; Genomic_DNA.
DR   RefSeq; YP_718856.1; -.
DR   GeneID; 4240132; -.
DR   GenomeReviews; CP000436_GR; HS_0644.
DR   KEGG; hso:HS_0644; -.
DR   NMPDR; fig|205914.1.peg.1368; -.
DR   HOGENOM; Q0I2Y9; -.
DR   OMA; Q0I2Y9; NQFIEPT.
DR   BioCyc; HSOM205914:HS_0644-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group ...; IEA:InterPro.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:HAMAP.
DR   GO; GO:0008655; P:pyrimidine salvage; IEA:HAMAP.
DR   HAMAP; MF_00551; -; 1.
DR   InterPro; IPR006083; PRK_URK.
DR   InterPro; IPR000764; Uridine_kinase.
DR   PANTHER; PTHR10285:SF6; Uridine_kin; 1.
DR   Pfam; PF00485; PRK; 1.
DR   PRINTS; PR00988; URIDINKINASE.
DR   TIGRFAMs; TIGR00235; udk; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    213       Uridine kinase.
FT                                /FTId=PRO_1000017880.
FT   NP_BIND      13     20       ATP (Potential).
SQ   SEQUENCE   213 AA;  24484 MW;  6A16E3E412086EEF CRC64;
     MSDQSCIIIA IAGASASGKS LIASTIHEEL CNELGCEEIG IVTEDSYYKD QTHLSFEERI
     KTNYDHPNSM DRDLLIQHLC DLKKGKAVDI PVYSYVEHTR TQEVTRFEPK KVIILEGILL
     LTDERIRQEV NMSVFVDTPL DICFIRRLQR DMEERGRSLQ SVIDQYKSTV RPMFLQFIEP
     SKQYADIVVP RGGKNRVAIN MLKVQIQHLL NNK
//