Reviewed, UniProtKB/Swiss-Prot Q0I239 (GLPB_HAES1)

Names and origin

Protein names

Recommended name:
    Anaerobic glycerol-3-phosphate dehydrogenase subunit B
      Short name=Anaerobic G-3-P dehydrogenase subunit B
      Short name=Anaerobic G3Pdhase B
    EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	HS_0513

Organism

Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)) [Complete proteome] [HAMAP]

Taxonomic identifier

205914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Histophilus

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity.
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP MF_00753
Subunit structure	Composed of a catalytic glpA/B dimer and of membrane bound glpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP MF_00753		PRO_1000046606

Sequences

	Sequence		Length	Mass (Da)
	Q0I239-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 65C87F49308B214D	FASTA	432	48,078
	10 20 30 40 50 60 MKFDVVIIGG GLAGLTCGIM LQQKGKCCAI INNGQSAMNF SSGSMDLLSQ LPNGEKINSF 70 80 90 100 110 120 EQGYDSLEEQ LPNHPYCLFG KQHVLQKAKQ FEQLIEKINL NVTGSYKQNH FRVTPLGGLH 130 140 150 160 170 180 RTWLSADCIP TMDLHDEHFG YQKITVLGIE GYHDFQPHLL AENLIQHPQF THCSITTALL 190 200 210 220 230 240 HLPELDQLRL TSREFRSVNI SQLLEHRLAF RELVQEIKQA SGDGEAIFLP ACFGLDNQDF 250 260 270 280 290 300 FNKLTLETGL NLYELPTLPP SLVGLRQHKK LKTYFEKLGG FILNGDKALR AVIEDQQVKQ 310 320 330 340 350 360 IYTQLHQEHG IFAEHFVLAS GSFFSNGLVS VFDRLLEPIF DVDMIGNSMI DIQNRLTWTA 370 380 390 400 410 420 RRFSSPQPYQ SAGVAINSCC QLKKSGQIIK NLYAAGNVIG GYNALELGCG SGVAVVTALT 430 VADNIIEAQN RV

References

[1]

"Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd." Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J. J. Bacteriol. 189:1890-1898(2007) [PubMed: 17172329] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000436 Genomic DNA. Translation: ABI24790.1.
RefSeq	YP_718724.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4239995.
GenomeReviews	Gene locus HS_0513 in contig CP000436_GR.
KEGG	hso:HS_0513.
NMPDR	fig|205914.1.peg.1406.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0I239.
OMA	Q0I239. TWLSQPF.
Enzyme and pathway databases
BioCyc	HSOM205914:HS_0513-MON.
Family and domain databases
HAMAP	MF_00753. [Tree]
InterPro	IPR009158. Anaerobic_glycerol3P_DH_bsu. IPR003953. FAD_bind2_N. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_HAES1

Accession

Primary (citable) accession number: Q0I239

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 3, 2006
Last modified:	June 16, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)