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Q0I061

- ASSY_SHESR

UniProt

Q0I061 - ASSY_SHESR

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Protein
Argininosuccinate synthase
Gene
argG, Shewmr7_0239
Organism
Shewanella sp. (strain MR-7)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei44 – 441ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei96 – 961Citrulline By similarity
Binding sitei101 – 1011Citrulline By similarity
Binding sitei126 – 1261ATP; via amide nitrogen By similarity
Binding sitei128 – 1281Aspartate By similarity
Binding sitei132 – 1321Aspartate By similarity
Binding sitei132 – 1321Citrulline By similarity
Binding sitei133 – 1331Aspartate By similarity
Binding sitei136 – 1361Citrulline By similarity
Binding sitei185 – 1851Citrulline By similarity
Binding sitei194 – 1941Citrulline By similarity
Binding sitei270 – 2701Citrulline By similarity
Binding sitei282 – 2821Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP60481:GHW6-257-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Shewmr7_0239
OrganismiShewanella sp. (strain MR-7)
Taxonomic identifieri60481 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001960: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Argininosuccinate synthaseUniRule annotation
PRO_0000263972Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi60481.Shewmr7_0239.

Structurei

3D structure databases

ProteinModelPortaliQ0I061.
SMRiQ0I061. Positions 12-406.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0I061-1 [UniParc]FASTAAdd to Basket

« Hide

MSIENKNTGV KKVVLAYSGG LDTSAIIPWL KETYDNCEII AFCADVGQGE    50
EELVGLTEKA LASGASECHI VDLKEEFVKD YIYPTMATGA IYEGTYLLGT 100
SMARPIIAKA QVEVARKVGA DALCHGCTGK GNDQVRFEGC FAALAPDLKV 150
IAPWREWTMQ SREDLLAYLA ERNIKTSASA TKIYSRDANA FHISHEGGEL 200
EDPWNEPSKG VWTLTADPED APNQAEYVSL EVEHGRVTKV NGEALTPYAA 250
LMKLNAIAAP HGVGRIDITE NRLVGMKSRG CYETPGGTVM FAALRAIEEL 300
VLDKTSRTWR EQVGAQMAHL VYDGRWFTPL CKSLLAASES LAESVNGEVV 350
VKLYKGHAIA VKKRSPNSLY SEAFATFGED QVYDQKHAEG FIRLYSLASR 400
IRALNAK 407
Length:407
Mass (Da):44,522
Last modified:October 3, 2006 - v1
Checksum:iF2228A36568C49D7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI41244.1.
RefSeqiYP_736301.1. NC_008322.1.

Genome annotation databases

EnsemblBacteriaiABI41244; ABI41244; Shewmr7_0239.
GeneIDi4256069.
KEGGishm:Shewmr7_0239.
PATRICi23585334. VBISheSp85603_0255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI41244.1 .
RefSeqi YP_736301.1. NC_008322.1.

3D structure databases

ProteinModelPortali Q0I061.
SMRi Q0I061. Positions 12-406.
ModBasei Search...

Protein-protein interaction databases

STRINGi 60481.Shewmr7_0239.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI41244 ; ABI41244 ; Shewmr7_0239 .
GeneIDi 4256069.
KEGGi shm:Shewmr7_0239.
PATRICi 23585334. VBISheSp85603_0255.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci SSP60481:GHW6-257-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-7.

Entry informationi

Entry nameiASSY_SHESR
AccessioniPrimary (citable) accession number: Q0I061
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 3, 2006
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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