Reviewed, UniProtKB/Swiss-Prot Q0HY38 (RLMG_SHESR)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase G
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rlmG
    23S rRNA m2G1835 methyltransferase

Gene names

Name:	rlmG
Ordered Locus Names:	Shewmr7_0968

Organism

Shewanella sp. (strain MR-7) [Complete proteome] [HAMAP]

Taxonomic identifier

60481 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01859
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 377	377	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366518

Sequences

	Sequence		Length	Mass (Da)
	Q0HY38-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: FB9AF05896C52B76	FASTA	377	41,624
	10 20 30 40 50 60 MTTQFSVAGI ELELFRYPAS QESNLQAWDA ADEHLINTLV EGGQTAVPTA IINDSFGALS 70 80 90 100 110 120 CALSRLTPDW PLNVETDART SFLGAEQNHH RNQLSMENLT WFTSRDALPS DLALVLMKLP 130 140 150 160 170 180 KNLTYFAHQL MRLSQVLPAG SKVLVGAKAK SINTSLLEVF AKYLGPASAS LAWKKTRVIT 190 200 210 220 230 240 CISDGKPRAL PKEITWDIPE FNLHISNLSN VFAANKLDIG ARIMLDNLPQ GDFKTIVDLG 250 260 270 280 290 300 CGNGVLGLRA AQLYPNADIH FIDDSEMAVA SAKANWANNQ LPAETGHFHW DDCMTHLPDG 310 320 330 340 350 360 VEPDLVLCNP PFHQGEAITD HIAWQMFLDA RRRLKNGGIL HIVGNRHLAY HVKLQRLFKN 370 CTTVASNGKF VILQAQK

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. MR-7." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000444 Genomic DNA. Translation: ABI41967.1.
RefSeq	YP_737024.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0HY38.
Genome annotation databases
GeneID	4255602.
GenomeReviews	Gene locus Shewmr7_0968 in contig CP000444_GR.
KEGG	shm:Shewmr7_0968.
NMPDR	fig|60481.10.peg.927.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0HY38.
OMA	NRHLGYH.
Family and domain databases
HAMAP	MF_01859. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_SHESR

Accession

Primary (citable) accession number: Q0HY38

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	October 3, 2006
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)