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Q0HXZ5 (RLMI_SHESR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase I
EC=2.1.1.191
Alternative name(s):
23S rRNA m5C1962 methyltransferase
rRNA (cytosine-C(5)-)-methyltransferase RlmI
Gene names
Name:rlmI
Ordered Locus Names:Shewmr7_1011
OrganismShewanella sp. (strain MR-7) [Complete proteome] [HAMAP]
Taxonomic identifier60481 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA By similarity. HAMAP-Rule MF_01857

Catalytic activity

S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1962) in 23S rRNA. HAMAP-Rule MF_01857

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01857.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmI family.

Contains 1 PUA domain.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandRNA-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

rRNA (cytosine) methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396Ribosomal RNA large subunit methyltransferase I HAMAP-Rule MF_01857
PRO_0000366264

Regions

Domain2 – 7978PUA

Sequences

Sequence LengthMass (Da)Tools
Q0HXZ5 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: A13F5FBEA691DDDC

FASTA39644,146
        10         20         30         40         50         60 
MAVRIKLKPG REKSLERRHP WVFSNGIHNV KGKLEPGDTV DVVAHDGHWL GRGAWSPESQ 

        70         80         90        100        110        120 
IQVRIWTFDR EEEIDREFFK RRILRAQAGR DDLIREQGLT GYRLIAAESD GLPGITIDKY 

       130        140        150        160        170        180 
ANVLVCQLLS MGADVWRDTI VDVLAELYPD CAIYERSDVD SRKKEGLAST MGLLHGSLPE 

       190        200        210        220        230        240 
MPVIIEENGI KIAVDVTKGH KTGFYLDQRD NRAMAARFVK GKSVLNCFCY TGTFGLYAAK 

       250        260        270        280        290        300 
AGAASIENVD VSALALDTAR LNMRVNGLND DNVHYNEADV FKLLRQYRDE GKTFDVIVLD 

       310        320        330        340        350        360 
PPKFADNKSQ LNGACRGYKD INMIALQLLN PGGVLLTFSC SGLMPADLFQ KIVADAALDA 

       370        380        390 
KREIQFIERL SQASDHPIGS AFPEGFYLKG LVARVW

« Hide

References

[1]"Complete sequence of chromosome 1 of Shewanella sp. MR-7."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MR-7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000444 Genomic DNA. Translation: ABI42010.1.
RefSeqYP_737067.1. NC_008322.1.

3D structure databases

ProteinModelPortalQ0HXZ5.
ModBaseSearch...

Protein-protein interaction databases

STRING60481.Shewmr7_1011.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI42010; ABI42010; Shewmr7_1011.
GeneID4255697.
KEGGshm:Shewmr7_1011.
PATRIC23586953. VBISheSp85603_1053.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1092.
HOGENOMHOG000266009.
KOK06969.
OMACSGLMTT.
ProtClustDBCLSK2462133.

Family and domain databases

HAMAPMF_01857. 23SrRNA_methyltr_I.
InterProIPR002478. PUA.
IPR015947. PUA-like_domain.
IPR023542. rRNA_lsu_MeTfrase_I.
IPR019614. SAM-dep_methyl-trfase.
[Graphical view]
PfamPF10672. Methyltrans_SAM. 1 hit.
[Graphical view]
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF88697. PUA-like. 1 hit.
PROSITEPS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLMI_SHESR
AccessionPrimary (citable) accession number: Q0HXZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: October 3, 2006
Last modified: May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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