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Q0HXA2

- GLSA_SHESR

UniProt

Q0HXA2 - GLSA_SHESR

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Protein

Glutaminase

Gene
glsA, Shewmr7_1254
Organism
Shewanella sp. (strain MR-7)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSSP60481:GHW6-1307-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Shewmr7_1254
OrganismiShewanella sp. (strain MR-7)
Taxonomic identifieri60481 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001960: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotationPRO_1000048362Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi60481.Shewmr7_1254.

Structurei

3D structure databases

ProteinModelPortaliQ0HXA2.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0HXA2-1 [UniParc]FASTAAdd to Basket

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MPEQALLEEV VDKVRPLLGQ GKVANYIPAL ANVDAGKLGI AVTTIDGETI    50
GAGDYLEPFS IQSISKVFSL TLALTLYEET EIWSRVGKEP SGHSFNSLVQ 100
VELERGKPRN PFINAGALVI ADLLQSRLGA PKHRMLELVR ALSQNDKVCF 150
DKQVADSEYQ HSARNAAIAY LMKSFGNFQG DVDTVLRTYF HYCALKMNCA 200
DLSRAMLYLA NRGKTLDGTE LISQVQTRQL NALLATSGLY DGAGEFAYRV 250
GMPGKSGVGG GIIAVIPGEL SVCVWSPELD NQGNSLAGTA MLEHLSQRLG 300
RSIF 304
Length:304
Mass (Da):32,925
Last modified:October 3, 2006 - v1
Checksum:i40DD255431CEECD4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI42253.1.
RefSeqiYP_737310.1. NC_008322.1.

Genome annotation databases

EnsemblBacteriaiABI42253; ABI42253; Shewmr7_1254.
GeneIDi4258179.
KEGGishm:Shewmr7_1254.
PATRICi23587477. VBISheSp85603_1293.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI42253.1 .
RefSeqi YP_737310.1. NC_008322.1.

3D structure databases

ProteinModelPortali Q0HXA2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 60481.Shewmr7_1254.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI42253 ; ABI42253 ; Shewmr7_1254 .
GeneIDi 4258179.
KEGGi shm:Shewmr7_1254.
PATRICi 23587477. VBISheSp85603_1293.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SSP60481:GHW6-1307-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-7.

Entry informationi

Entry nameiGLSA_SHESR
AccessioniPrimary (citable) accession number: Q0HXA2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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