Reviewed, UniProtKB/Swiss-Prot Q0HWV8 (GLMM2_SHESR)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase 2
    EC=5.4.2.10

Gene names

Name:	glmM2
Ordered Locus Names:	Shewmr7_1398

Organism

Shewanella sp. (strain MR-7) [Complete proteome] [HAMAP]

Taxonomic identifier

60481 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 450	450	Phosphoglucosamine mutase 2 HAMAP MF_01554		PRO_0000305678
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0HWV8-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: CC05BCA27B679295	FASTA	450	47,824
	10 20 30 40 50 60 MSRKYFGTDG VRGKVGTFPI TPDFAMKLGW AAGTVLASTG TKEVLIGKDT RISGYMLESA 70 80 90 100 110 120 MEAGFSAAGV NVALIGPMPT PAVAYLASTF RADAGVVISA SHNPFYDNGI KFFSNTGTKL 130 140 150 160 170 180 NDAQELEIEA LLEQALEHNA LQCVASEKLG KVRRIDDAAG RYIEFCKGTF PNHLSLAGLK 190 200 210 220 230 240 IVVDSAHGAA YHIAPNVYRE LGAEVISIND KPNGVNINDH CGATHLDSLQ SAVMIHEADL 250 260 270 280 290 300 GIALDGDADR VMFVDHNGHV VDGDEILFIL AQAAYQKGEM QGGVVGTLMS NLGLELALKQ 310 320 330 340 350 360 MGIPFLRAKV GDRYVVEQLK ETGWQLGGEG SGHILSLQHA STGDGIVASL QVLKAILESG 370 380 390 400 410 420 KRLAELKAGM TKLPQVLINV RLTSGSADSI LSKDSVKQAV ITAEEVLGNQ GRVLLRKSGT 430 440 450 EPLIRVMVES TDISLTQQQA EYIAQAVKVA

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. MR-7." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000444 Genomic DNA. Translation: ABI42397.1.
RefSeq	YP_737454.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0HWV8.
Genome annotation databases
GeneID	4258567.
GenomeReviews	Gene locus Shewmr7_1398 in contig CP000444_GR.
KEGG	shm:Shewmr7_1398.
NMPDR	fig|60481.10.peg.1330.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0HWV8.
OMA	NTIPEDL.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM2_SHESR

Accession

Primary (citable) accession number: Q0HWV8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	October 3, 2006
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)