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Q0HW30

- Q0HW30_SHESR

UniProt

Q0HW30 - Q0HW30_SHESR

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Shewmr7_1681

Organism
Shewanella sp. (strain MR-7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (03 Oct 2006)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471SubstrateUniRule annotation
    Sitei257 – 2571Critical for catalysisUniRule annotation
    Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
    Sitei422 – 4221Critical for catalysisUniRule annotation
    Binding sitei549 – 5491SubstrateUniRule annotation
    Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation
    Metal bindingi554 – 5541Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciSSP60481:GHW6-1765-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Shewmr7_1681Imported
    OrganismiShewanella sp. (strain MR-7)Imported
    Taxonomic identifieri60481 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000001960: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi60481.Shewmr7_1681.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0HW30.
    SMRiQ0HW30. Positions 5-739.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0HW30-1 [UniParc]FASTAAdd to Basket

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    MKDNSPTIIY TETDEAPALA TLSLLPIIKT FTDAAGVAVE TRDISLSGRV    50
    IANFPEKLTD AQKIGDHLAE LGELANQPEA NIIKLPNISA SIPQLKACIL 100
    ELQQKGYDIP NYPDEPKTDE EKSIKARYDK IKGSAVNPVL REGNSDRRAP 150
    LSVKNFAKKN PHSMGKWSKE SQSHVAHMSE GDFYGSEQSV TLANADTVNI 200
    VLSQKDGQEV VLKSGLKLLA GEIIDASVMS KKALVSFFER EIANAKAENV 250
    LLSLHLKATM MKVSDPIMFG HAVKVFFKPV FDKHASLFAE LGVDVNNGFG 300
    DVYAKIASLP ADVRAQIEAD IAAVYAERPA LAMVDSDKGI TNLHVPSDII 350
    IDASMPAAIR SSGQMWGPDG KLHDTKALIP DRCYAGVYQE TIAFCKEHGA 400
    FDPSTMGSVP NVGLMAQKAE EYGSHDKTFE IPADGVVNVI DASGKVLMSH 450
    NVEAGDIWRM CQVKDAPIRD WVKLAVRRAR LSNTPAVFWL DANRAHDAQL 500
    IAKVKQYLPE HDTSGLEISI MSPEEATRFS LVRIKEGKDT ISVTGNVLRD 550
    YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVEKEGH 600
    LRWDSLGEFL ALAASLEHLS QTVGNPKAQV LADTLDQAIG QFLDSNKSPS 650
    RRVGELDNRG SHFYLAMYWA QALAAQTKDE QLQAHFIPLA HALAANEQVI 700
    VAELNNAQGA PVDLGGYYRL DAAKAEKAMR PSETLNKLLI A 741
    Length:741
    Mass (Da):80,486
    Last modified:October 3, 2006 - v1
    Checksum:iFB554DEA78B9D15C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000444 Genomic DNA. Translation: ABI42675.1.
    RefSeqiWP_011625938.1. NC_008322.1.
    YP_737732.1. NC_008322.1.

    Genome annotation databases

    EnsemblBacteriaiABI42675; ABI42675; Shewmr7_1681.
    GeneIDi4256315.
    KEGGishm:Shewmr7_1681.
    PATRICi23588433. VBISheSp85603_1740.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000444 Genomic DNA. Translation: ABI42675.1 .
    RefSeqi WP_011625938.1. NC_008322.1.
    YP_737732.1. NC_008322.1.

    3D structure databases

    ProteinModelPortali Q0HW30.
    SMRi Q0HW30. Positions 5-739.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 60481.Shewmr7_1681.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABI42675 ; ABI42675 ; Shewmr7_1681 .
    GeneIDi 4256315.
    KEGGi shm:Shewmr7_1681.
    PATRICi 23588433. VBISheSp85603_1740.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci SSP60481:GHW6-1765-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MR-7Imported.

    Entry informationi

    Entry nameiQ0HW30_SHESR
    AccessioniPrimary (citable) accession number: Q0HW30
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2006
    Last sequence update: October 3, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3